Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Development of Analytical Methods01:21

Development of Analytical Methods

2.6K
An analytical methodology can be divided into four sequential steps: technique, method, procedure, and protocol. A technique is a scientific principle that rationalizes a specific phenomenon through chemical measurements. Adapting a technique for analyzing a sample of interest is termed a method. The procedure outlines the directions for performing the analysis via an analytical method. The protocol is the detailed guidelines on the procedure, which should be strictly followed to obtain the...
2.6K
Sample Preparation for Analysis: Overview01:21

Sample Preparation for Analysis: Overview

3.9K
Sample preparation is an essential step in the analytical process. It involves preparing a sample so that it can be analyzed accurately. The goal is to extract the analyte, the substance you want to measure, from the sample while removing any components that may interfere with the analysis. Sample preparation techniques vary depending on the physical state of the sample.
Bulk or large solid samples are typically reduced in size using grinding, crushing, or milling techniques to increase the...
3.9K
Therapeutic Drug Monitoring: Drug Analysis Methods01:26

Therapeutic Drug Monitoring: Drug Analysis Methods

231
Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood or body tissues to tailor drug therapy effectively. This monitoring is critical for managing drugs with narrow therapeutic indices like digoxin and phenytoin, ensuring they are both safe and effective. For instance, monitoring theophylline levels in asthma patients involves precision and sensitivity to adjust doses according to individual responses to therapy, ensuring efficacy and...
231
Qualitative Analysis01:10

Qualitative Analysis

1.5K
Qualitative analysis is the process of identifying elements, ions, or compounds in an unknown sample. It is the first and most fundamental type of analysis based on the hierarchy of analytical goals. This hierarchy is significant as it provides a structured approach to scientific research, with qualitative analysis serving as the initial step, providing essential information before moving on to quantitative or other forms of analysis.
There are two main approaches to qualitative analysis:...
1.5K
Drug Concentrations: Measurements01:23

Drug Concentrations: Measurements

1.2K
Drug concentration is the quantity of a drug present in a biological sample. Measuring drug amounts in biological samples allows the clinician to understand how a drug is absorbed, distributed, metabolized, and excreted. Samples can be obtained through invasive or non-invasive methods. Invasive techniques involve surgical or parenteral interventions to gather blood, cerebrospinal fluid, or tissue biopsy. Conversely, non-invasive approaches provide samples like urine, feces, and saliva.
Plasma...
1.2K
Pharmaceutical Alternatives: Polymorphic Form-Related and Particle Size-Related Therapeutic Nonequivalence01:27

Pharmaceutical Alternatives: Polymorphic Form-Related and Particle Size-Related Therapeutic Nonequivalence

198
Changes in polymorphic forms can significantly influence the bioavailability of poorly soluble drugs. Although the FDA defines pharmaceutical equivalence based on having the same active ingredient, dosage form, and route of administration, it does not automatically disqualify products with different polymorphic forms. This means two products with different polymorphs can still be deemed pharmaceutically equivalent. However, polymorphic differences can affect properties like wettability,...
198

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Affordable Arsenic Detection Device Using Handmade Lokta Paper for Decentralized and Sustainable Manufacturing.

Journal of analytical methods in chemistry·2026
Same author

Exploring curriculum gaps in pharmacy education in Nepal: A pilot study and recommendations for reform.

Currents in pharmacy teaching & learning·2026
Same author

Impact of meteorological drivers on air quality index: A case study from Delhi.

Environmental pollution (Barking, Essex : 1987)·2025
Same author

Smartphone-Assisted Thin-Layer Chromatography for Rapid Quality Screening of Metformin.

Advances in pharmacological and pharmaceutical sciences·2025
Same author

Distribution and characteristics of microplastics in fluvial sediments from the Koshi River Basin, Nepal.

Environmental pollution (Barking, Essex : 1987)·2025
Same author

Prevalence and Trends in Pediatric-Onset Chronic Conditions in the United States, 1999-2018.

Academic pediatrics·2025

Related Experiment Video

Updated: Feb 22, 2026

Method Development for Contactless Resonant Cavity Dielectric Spectroscopic Studies of Cellulosic Paper
05:40

Method Development for Contactless Resonant Cavity Dielectric Spectroscopic Studies of Cellulosic Paper

Published on: October 4, 2019

6.5K

Advances in paper-analytical methods for pharmaceutical analysis.

Niraj Sharma1, Toni Barstis2, Basant Giri1

  • 1Center for Analytical Sciences, Kathmandu Institute of Applied Sciences, PO Box 23002, Kalanki-13, Kathmandu, Nepal.

European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences
|September 26, 2017
PubMed
Summary
This summary is machine-generated.

Paper microfluidic devices offer a cost-effective, portable solution for pharmaceutical screening. These devices leverage inexpensive paper substrates and adaptable methods for reliable analysis, especially in resource-limited settings.

Keywords:
Detection methodsDrug deliveryFabrication techniquesLow quality pharmaceuticalsResource-limited settings

More Related Videos

An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment
08:59

An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment

Published on: December 3, 2020

8.7K
Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays
11:33

Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays

Published on: March 9, 2017

16.5K

Related Experiment Videos

Last Updated: Feb 22, 2026

Method Development for Contactless Resonant Cavity Dielectric Spectroscopic Studies of Cellulosic Paper
05:40

Method Development for Contactless Resonant Cavity Dielectric Spectroscopic Studies of Cellulosic Paper

Published on: October 4, 2019

6.5K
An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment
08:59

An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment

Published on: December 3, 2020

8.7K
Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays
11:33

Fabrication of Three-dimensional Paper-based Microfluidic Devices for Immunoassays

Published on: March 9, 2017

16.5K

Area of Science:

  • Analytical Chemistry
  • Materials Science
  • Biomedical Engineering

Background:

  • Paper microfluidic devices offer advantages over traditional microfluidic systems due to their low cost, ease of fabrication, and portability.
  • The paper substrate is versatile and can be modified for various applications, enabling the creation of milli- to micro-scale patterns.
  • Established chemical and biological methods can be adapted for use on paper, facilitating portable analyses in resource-limited environments.

Purpose of the Study:

  • To review the fabrication processes of paper microfluidic devices.
  • To present various detection techniques applicable to paper-based analytical devices.
  • To highlight the applications of paper microfluidic devices in pharmaceutical screening.

Main Methods:

  • Review of existing literature on paper microfluidic device fabrication.
  • Analysis of different detection strategies employed in paper-based assays.
  • Compilation of case studies demonstrating the use of paper devices for pharmaceutical quality control.

Main Results:

  • Paper devices provide a fast, cost-effective platform using minimal reagents and samples.
  • The adaptability of paper substrates allows for diverse applications in analytical screening.
  • Paper microfluidic devices have proven reliable for screening low-quality pharmaceuticals.

Conclusions:

  • Paper microfluidic devices are emerging as robust analytical tools for pharmaceutical screening.
  • Their portability and low cost make them ideal for field applications and resource-limited settings.
  • Further development in fabrication and detection techniques will enhance their utility in pharmaceutical quality assurance.