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Updated: Feb 22, 2026

Operating Transverse Aortic Constriction with Absorbable Suture to Obtain Transient Myocardial Hypertrophy
Published on: September 9, 2020
Transaortic septal myectomy: techniques and pitfalls
Anthony Ralph-Edwards1, Rachel D Vanderlaan1, Pietro Bajona2,3
1Division of Cardiovascular Surgery, Toronto General Hospital, University of Toronto, Toronto, ON, Canada.
Insights
Hypertrophic cardiomyopathy (HCM) can cause outflow tract obstruction, requiring treatment. Surgical myectomy is the gold standard, offering better long-term results and fewer complications than other therapies for this common congenital heart disease.
Area of Science:
- Cardiology
- Genetics
- Congenital Heart Disease
Background:
- Hypertrophic cardiomyopathy (HCM) is a common genetic heart condition affecting up to 1 in 200 individuals.
- Left ventricular outflow tract (LVOT) obstruction in HCM necessitates treatment to alleviate symptoms and prevent sudden cardiac death.
Purpose of the Study:
- To compare the efficacy and safety of surgical myectomy versus percutaneous ablation for treating obstructive HCM.
- To establish surgical myectomy as the gold standard for managing subaortic obstruction in HCM.
Main Methods:
- Review of existing literature on treatments for obstructive HCM.
- Analysis of complication rates and long-term effectiveness of surgical myectomy and percutaneous ablation.
- Evaluation of the degree and duration of LVOT obstruction reduction for both procedures.
Main Results:
- Both surgical myectomy and percutaneous ablation are effective in treating LVOT obstruction.
- Surgical myectomy demonstrates a significantly lower complication rate compared to percutaneous ablation.
- Myectomy provides a more complete and sustained reduction in LVOT obstruction.
Conclusions:
- Surgical myectomy is the preferred and gold standard treatment for obstructive hypertrophic cardiomyopathy.
- Patients with obstructive HCM benefit from myectomy due to its superior safety and long-term efficacy profile.
Abstract:
Hypertrophic cardiomyopathy (HCM) is the most common congenital cardiac disease, affecting up to 1 in 200 individuals. When it causes left ventricular outflow tract (LVOT) obstruction, treatment is indicated to reduce symptoms and the risk of sudden cardiac death. Pharmacologic therapy is the first line treatment, however if it fails, surgical myectomy or percutaneous ablation of the hypertrophic myocardium are the standard therapies to eliminate subaortic obstruction. Both surgical myectomy and percutaneous ablation have been demonstrated as safe and effective treatments; however, myectomy is the gold standard with a significantly lower complication rate and more complete and longstanding reduction of LVOT obstruction.
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