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The caffeoyl phenylethanoid glycosides from Lindernia ruellioides and their anti-HBV effects
Jing-Chen Wei1,2, Peng-Cheng Wang1, Xian-Li Zhou1
1a College of Pharmacy , Guilin Medical University , Guilin 541004 , China.
Abstract:
Five caffeoyl phenylethanoid glycosides, including two new ones linderruelliosides A (1) and B (2), were isolated from the leaves and stems of Lindernia ruellioides. Their structures were elucidated on the basis of spectroscopic methods, including extensive NMR and MS spectra. In addition, all these compounds were tested for their anti-HBV activity. Compounds 1, 3, and 4 showed anti-HBV activities, with IC50 values of 54.87, 30.74, and 69.02 μM for HBsAg and 26.70, 5.17, and 7.08 μM for HBeAg, respectively.
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