Related Experiment Video
Updated: Feb 22, 2026

Investigating the Phagocytosis of Leishmania using Confocal Microscopy
Published on: July 29, 2021
New insights to structure and immunological features of Leishmania lipophosphoglycan3
Maryam Hosseini1, Mostafa Haji-Fatahaliha1, Abolfazl Miahipour2
1Stem Cell and Regenerative Medicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Abstract:
Leishmaniasis is a major public infectious disease caused by the genus Leishmania. No effective drug or vaccination strategy for leishmaniasis has been designed yet. Several intracellular Leishmania antigens have been recognized to serve in vaccination, ensuring long-lasting protection against Leishmania infection. Lipophosphoglican 3 (LPG3) as a member of the heat shock protein 90 family involves in the synthesis of lipophosphoglycan (LPG) and implicates in parasite virulence. Regarding the immunological properties of LPG3 particularly its N-terminal fragment, it would be considered as a favourable adjuvant in Leishmania vaccination.
Related Concept Videos
Formation of Lipopolysaccharides
Membrane Lipids
Phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, and sphingomyelin are the most common phospholipids present in mammalian membranes. At physiological pH, phosphatidylserine is negatively charged, while the other three...
Structure of Lipids
Outer Layers of the Cell Envelope
Phosphoinositides and PIPs
Different phosphoinositides are synthesized and recruited on the cytosolic face of the plasma membrane. The localization of specific phosphoinositides concentrated in separate membrane...
Asymmetric Lipid Bilayer

