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Role of Skin in Vitamin D Synthesis01:23

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The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
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Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
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Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
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A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
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Vitamin D supplementation.

Ruth Dobson1, Hannah R Cock1,2, Peter Brex3

  • 1Department of Neurology, St George's Hospital NHS Trust, London, UK.

Practical Neurology
|September 27, 2017
PubMed
Summary
This summary is machine-generated.

Neurologists are increasingly interested in vitamin D testing and supplementation beyond bone health. This discussion focuses on multiple sclerosis and epilepsy, outlining rationale for testing serum 25-hydroxyvitamin D and supplementation strategies.

Keywords:
epilepsymultiple sclerosisosteoporosissupplementationvitamin D

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Area of Science:

  • Neurology
  • Endocrinology
  • Nutritional Science

Background:

  • Current UK vitamin D recommendations primarily address bone health.
  • Emerging evidence suggests vitamin D's role in neurological conditions.
  • Vitamin D deficiency is linked to increased complications in multiple sclerosis and epilepsy.

Discussion:

  • Neurologists' approach to vitamin D testing and supplementation for neurological patients.
  • Rationale for testing serum 25-hydroxyvitamin D concentrations.
  • Personal supplementation practices supported by available evidence.

Key Insights:

  • Vitamin D's significance extends beyond bone health, impacting neurological disorders.
  • Testing serum 25-hydroxyvitamin D is crucial for identifying deficiency.
  • Evidence-based supplementation strategies are essential for managing associated risks.

Outlook:

  • Further research into vitamin D's role in neurological disease management.
  • Integration of vitamin D assessment into routine neurological care.
  • Optimizing supplementation protocols for improved patient outcomes.