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Updated: Feb 22, 2026

Author Spotlight: Regenerative Roles of Muscle Proteins at Neuromuscular Junction Post-Nerve Injury
Published on: November 1, 2024
Levator Palpebrae Superioris Muscle Direct Neurotization
Alexánder Cárdenas-Mejía1, Damián Palafox, Daniela Téllez-Palacios
1*Plastic and Reconstructive Surgery Department, Hospital General "Dr. Manuel Gea González;" †Neurophysiology Department, Hospital Angeles Pedregal ‡Opthalmology Department, Hospital General "Dr. Manuel Gea González," Mexico City, Mexico.
Abstract:
Direct muscle neurotization has been proved to be a feasible technique for facial reanimation microsurgical procedures. Direct muscle neurotization is performed by implanting the interposition nerve graft directly into the substance of the muscle. The authors present the case of a 36-year-old male patient with upper eyelid dysfunction secondary to facial trauma. The levator palpebrae superioris muscle was macroscopically unaffected; however, neurophysiological test proved a selective denervation of the CN III motor branch to the levator palpebrae superioris muscle. Direct muscle neurotization was performed by means of 2 separate nerve procedures. The authors have made follow-up for 3 months after surgery. The authors have noted development of upper eyelid movement meaning adequate function of the neurotized muscle. The authors believe that this procedure could be integrated into the surgical options to treat selective nerve injuries should the right patient is encountered.
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