Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

2.9K
Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
2.9K
Atomic Absorption Spectroscopy: Atomization Methods01:25

Atomic Absorption Spectroscopy: Atomization Methods

1.7K
Atomic Absorption Spectroscopy (AAS) atomizes samples through flame atomization or electrothermal atomization. Flame atomization typically involves a nebulizer and spray chamber assembly to combine the sample with a fuel–oxidant mixture, creating a fine aerosol mist that enters a burner. Typically, the fuel and oxidant are combined in an approximately stoichiometric ratio. However, for atoms that are easily oxidized, a fuel-rich mixture may be more advantageous. Only about 5% of the...
1.7K
Atomic Force Microscopy01:08

Atomic Force Microscopy

4.6K
Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...
4.6K
Atomic Absorption Spectroscopy: Overview01:27

Atomic Absorption Spectroscopy: Overview

3.7K
Atomic absorption spectroscopy (AAS) is a technique used to analyze elements by measuring electromagnetic radiation (EMR) absorbed by atoms, which causes them to transition to a higher-energy orbit. The most crucial step in AAS is atomization, where the analyte is converted into gas-phase atoms, typically through a flame or furnace. Some of these atoms become thermally excited in the flame, while most remain in the ground state.
When irradiated by EMR of a particular wavelength, these...
3.7K
Atomic Emission Spectroscopy: Overview01:20

Atomic Emission Spectroscopy: Overview

3.9K
Atomic emission spectroscopy (AES) is an analytical technique used to determine the elemental composition of a sample by analyzing the light emitted from excited atoms. In AES, atoms in a sample are excited to higher energy levels by thermal energy from high-temperature sources, such as plasma, arcs, or sparks. When these excited atoms return to lower energy states, they emit light at specific wavelengths characteristic of each element. The resulting atomic emission spectrum, which consists of...
3.9K
Extraction: Advanced Methods00:56

Extraction: Advanced Methods

1.2K
Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Orientational Switching as an Extra Degree of Freedom in Self-Assembled C<sub>70</sub> and Octanethiol on Au(111).

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Mott state of flat bands in a 2D metal-organic Kagome framework.

National science review·2026
Same author

Synthetic data-driven deep learning for label-free autonomous atomic force microscopy.

Nature communications·2026
Same author

Beyond Optimization: Exploring Novelty Discovery in Autonomous Experiments.

ACS nanoscience Au·2026
Same author

Molecular Simulation Studies of CO<sub>2</sub>-CH<sub>4</sub>-H<sub>2</sub>O Ternary Geological Fluids in Clay Confinements.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Unveiling Swift Heavy Ion Track Morphology in Sr-Based High-Entropy Perovskites.

ACS nano·2026
Same journal

Vertically Stacked Indium Gallium Zinc Oxide-Based Three-Dimensional Integrated Circuits.

ACS nano·2026
Same journal

Tunable Nanoparticle Thin-Film Reveals Distance Dependence of Auger-Mediated Radiation Enhancement in Diffuse Midline Glioma.

ACS nano·2026
Same journal

G-Quadruplex Network Engineering in Ionogels: Realizing Robust Biosensing Interfaces for Plant Electrophysiology.

ACS nano·2026
Same journal

Announcing the 2026 <i>ACS Nano</i> Lectureship and <i>ACS Nano</i> Impact Award Laureates.

ACS nano·2026
Same journal

Ultrafast Self-Assembly of Zeolitic Imidazolate Framework-8 Enables Antibody Orientation for Ultrasensitive Lateral Flow Immunoassays.

ACS nano·2026
Same journal

Interfacial Salt Engineering with Alkali and Ammonium Additives for Stable Pure-Blue Perovskite Light-Emitting Diodes and Micropatterned Displays.

ACS nano·2026
See all related articles

Related Experiment Video

Updated: Feb 22, 2026

Picometer-Precision Atomic Position Tracking through Electron Microscopy
15:04

Picometer-Precision Atomic Position Tracking through Electron Microscopy

Published on: July 3, 2021

8.4K

Knowledge Extraction from Atomically Resolved Images.

Lukas Vlcek1,2, Artem Maksov3, Minghu Pan4

  • 1Chemical Sciences Division, Oak Ridge National Laboratory , Oak Ridge Tennessee 37831, United States.

ACS Nano
|September 28, 2017
PubMed
Summary
This summary is machine-generated.

This study introduces a new framework to extract physical interaction parameters from atomic configurations in microscopy images. This method unlocks hidden thermodynamic information, advancing materials science research.

Keywords:
STMimage analysismodeloptimizationsimulationstatistical distance

More Related Videos

Whole-cell Super-Resolution Imaging via DNA-PAINT on a Spinning Disk Confocal with Optical Photon Reassignment
07:12

Whole-cell Super-Resolution Imaging via DNA-PAINT on a Spinning Disk Confocal with Optical Photon Reassignment

Published on: January 6, 2026

313
Photoelectron Imaging of Anions Illustrated by 310 Nm Detachment of F&#8722;
06:53

Photoelectron Imaging of Anions Illustrated by 310 Nm Detachment of F−

Published on: July 27, 2018

9.2K

Related Experiment Videos

Last Updated: Feb 22, 2026

Picometer-Precision Atomic Position Tracking through Electron Microscopy
15:04

Picometer-Precision Atomic Position Tracking through Electron Microscopy

Published on: July 3, 2021

8.4K
Whole-cell Super-Resolution Imaging via DNA-PAINT on a Spinning Disk Confocal with Optical Photon Reassignment
07:12

Whole-cell Super-Resolution Imaging via DNA-PAINT on a Spinning Disk Confocal with Optical Photon Reassignment

Published on: January 6, 2026

313
Photoelectron Imaging of Anions Illustrated by 310 Nm Detachment of F&#8722;
06:53

Photoelectron Imaging of Anions Illustrated by 310 Nm Detachment of F−

Published on: July 27, 2018

9.2K

Area of Science:

  • Materials Science
  • Surface Science
  • Statistical Mechanics

Background:

  • Scanning transmission electron microscopy and scanning tunneling microscopy (STM) have achieved routine atomically resolved imaging.
  • Integrating atomically resolved data with generative models to extract thermodynamic information is currently unavailable.
  • Microscopic driving forces encoded in atomic configurations remain largely unutilized.

Purpose of the Study:

  • To develop a universal framework for extracting physical interaction parameters from atomically resolved images.
  • To consistently utilize information from atomic configurations obtained via microscopy.
  • To reveal local thermodynamics and microscopic driving forces encoded in observed atomic structures.

Main Methods:

  • A framework based on statistical distance minimization is presented.
  • The method consistently utilizes atomic configurations from atomically resolved images.
  • Application illustrated using a scanning tunneling microscopy (STM) image of a FeSexTe1-x superconductor.

Main Results:

  • Meaningful physical interaction parameters were extracted from atomic configurations.
  • The segregation of chalcogen atoms in FeSexTe1-x was investigated using a nonideal interacting solid solution model.
  • The framework effectively utilizes microscopic degrees of freedom sampled in atomically resolved images.

Conclusions:

  • A universal method is established for extracting physical insights from atomic-resolution microscopy data.
  • The framework enables the extraction of thermodynamic information previously hidden in atomic configurations.
  • The method can be extended using Bayesian inference for unbiased model selection and uncertainty quantification.