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Updated: Feb 22, 2026

Intratracheal Inoculation of Fischer 344 Rats with Francisella tularensis
Published on: September 30, 2017
First case of severe pneumonic tularemia in an immunocompetent patient in the Netherlands
K C E Sigaloff1, P K Chung, J Koopmans
1Department of Infectious Diseases, Leiden University Medical Center, Leiden, the Netherlands.
Abstract:
Tularemia is a zoonosis caused by different subspecies of the Gram-negative bacterium Francisella tularensis. We report the first case in the Netherlands of pneumonic tularemia caused by the F. tularensis subspecies holarctica after probable occupational inhalation of contaminated aerosols. Notification of cases of tularemia has been mandatory by law in the Netherlands since 1 November 2016.
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