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Updated: Feb 22, 2026
Preparation and Photoacoustic Analysis of Cellular Vehicles Containing Gold Nanorods
Published on: May 2, 2016
Nitric oxide-activatable gold nanoparticles for specific targeting and photo-thermal ablation of macrophages
Junghong Park1, Swapan Pramanick, Jinhwan Kim
1Center for Self-assembly and Complexity, Institute for Basic Science, Pohang 790-784, Korea.
Abstract:
In this study, we designed NO-activatable gold nanoparticles (NAM-AuNPs) for specific targeting and photo-thermal ablation of macrophages. The gold nanoparticles showed aggregation behavior in response to NO solution as well as endogenous NO secreted from activated macrophages. Following NIR irradiation, significant cytotoxicity was observed in activated RAW 264.7 cells treated with NAM-AuNPs.
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