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Updated: Feb 22, 2026

Phage Phenomics: Physiological Approaches to Characterize Novel Viral Proteins
Published on: June 11, 2015
WIsH: who is the host? Predicting prokaryotic hosts from metagenomic phage contigs
Clovis Galiez1, Matthias Siebert1, François Enault2
1Quantitative and Computational Biology Group, Max-Planck Institute for Biophysical Chemistry, 37077?Göttingen, Germany.
Summary:
WIsH predicts prokaryotic hosts of phages from their genomic sequences. It achieves 63% mean accuracy when predicting the host genus among 20 genera for 3 kbp-long phage contigs. Over the best current tool, WisH shows much improved accuracy on phage sequences of a few kbp length and runs hundreds of times faster, making it suited for metagenomics studies.
Availability And Implementation:
OpenMP-parallelized GPL-licensed C ++ code available at https://github.com/soedinglab/wish.
Contact:
clovis.galiez@mpibpc.mpg.de or soeding@mpibpc.mpg.de.
Supplementary Information:
Supplementary data are available at Bioinformatics online.
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