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Bullous Skin Manifestations of Mycoplasma pneumoniae Infection: A Case Series

Senthil Velan Bhoopalan1, Vonita Chawla1, Mary Beth Hogan1

  • 1University of Nevada, Las Vegas Campus, Las Vegas, NV, USA.

Journal of Investigative Medicine High Impact Case Reports
|September 30, 2017
PubMed

Insights

Bullous skin lesions in children are rare but can be caused by Mycoplasma pneumoniae infections. Early diagnosis and treatment with corticosteroids or immunoglobulin can effectively manage these Mycoplasma-related skin manifestations.

Area of Science:

  • Pediatrics
  • Dermatology
  • Infectious Diseases

Background:

  • Bullous skin lesions are uncommon in pediatric patients.
  • Mycoplasma infections are typically associated with papular skin rashes, not blistering lesions.
  • Mycoplasma pneumoniae is a prevalent respiratory pathogen in children and adults.

Purpose of the Study:

  • To report cases of bullous skin lesions in children associated with Mycoplasma pneumoniae infection.
  • To increase awareness of this rare presentation of Mycoplasma pneumoniae.
  • To review the pathophysiology, diagnosis, and management of Mycoplasma-induced skin manifestations.

Main Methods:

  • Case report of two pediatric patients with serology-confirmed Mycoplasma infection.
  • Clinical presentation of bullous skin lesions described.
  • Treatment response to corticosteroids and intravenous immunoglobulin documented.

Main Results:

  • Two children presented with significant bullous skin lesions.
  • Both patients had serological evidence of Mycoplasma infection.
  • Treatment with corticosteroids was effective for both patients; one required intravenous immunoglobulin.

Conclusions:

  • Mycoplasma pneumoniae infection should be considered in the differential diagnosis of bullous skin lesions in children.
  • Prompt recognition and appropriate treatment can lead to favorable outcomes.
  • Further research into the mechanisms and optimal management of these dermatological manifestations is warranted.
Keywords:
IVIGMycoplasma pneumoniaeStevens-Johnson syndromeblistersbullouscorticosteroids

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