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Sydnone-alkyne cycloaddition: applications in synthesis and bioconjugation

Elodie Decuypère1, Lucie Plougastel, Davide Audisio

  • 1Service de Chimie Bio-organique et Marquage DRF-JOLIOT-SCBM, CEA, Université Paris-Saclay, 91191 Gif-sur-Yvette, France. frederic.taran@cea.fr.

Chemical Communications (Cambridge, England)
|September 30, 2017
PubMed
Summary

Sydnones, versatile mesoionic compounds, are increasingly used in cycloaddition reactions. Recent advances focus on regiocontrol and milder conditions, expanding their synthetic and biorthogonal chemistry applications.

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