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Updated: Feb 22, 2026

Murine Fetal Echocardiography
Published on: February 15, 2013
Two Cases of Prenatally Diagnosed Membranous and Muscular Ventricular Septal Aneurysms
Olga Ivanitskaya1, Elena Andreeva1, Natalia Odegova1
1Department of Medical Genetics, Moscow Regional Research Institute of Obstetrics and Gynecology, Moscow, Russia.
Abstract:
A ventricular septal aneurysm is a rare heart defect located in the muscular or membranous part of the septum. Muscular ventricular septal aneurysms are usually isolated, with a favorable prognosis. Membranous ventricular septal aneurysms are often associated with other heart anomalies, could result in serious complications, and may require surgical treatment. We describe 2 cases of prenatally diagnosed ventricular septal aneurysms: an isolated membranous ventricular septal aneurysm with a good outcome, which was initially misdiagnosed as an atrioventricular septal defect; and a muscular ventricular septal aneurysm associated with a hypoplastic aortic arch and severe hydrocephaly, which resulted in termination of the pregnancy. To our knowledge, the combination of a muscular ventricular septal aneurysm with an extracardiac anomaly has not been reported previously.
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