Amyopathic dermatomyositis with plantar keratoderma responding to methotrexate therapy

Amyopathic dermatomyositis (ADM) represents a substantial subset of dermatomyositis (DM). Patients with this symptom of the disorder may present initially to a dermatologist. Amyopathic dermatomyositis shares cutaneous findings with DM and both overlap and differ with respect to other key disease characteristics, including autoantibody profile, associated lung disease, and malignancy risk. Plantar keratoderma is a rare skin finding in DM. We report a case of ADM uniquely marked by the finding of plantar keratoderma, which resolved with oral methotrexate therapy.