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Related Concept Videos

Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

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Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
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Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...
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Ezocgabine or retigabine, an antiepileptic drug of remarkable efficacy, has revolutionized the management of seizures. It is a potassium channel activator, explicitly targeting the family of Q subtype potassium channels. It enhances the transmembrane potassium currents, regulating neuronal excitability. This action stabilizes the resting membrane potential, a pivotal factor in mitigating the hyperexcitability that characterizes epilepsy.
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Long-term Continuous EEG Monitoring in Small Rodent Models of Human Disease Using the Epoch Wireless Transmitter System
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New Developments in Refractory Status Epilepticus.

Sudhir Datar1

  • 1Section of Neurocritical Care, Departments of Neurology and Anesthesiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA.

Neurologic Clinics
|October 1, 2017
PubMed
Summary
This summary is machine-generated.

Status epilepticus (SE) is a medical emergency requiring prompt treatment. Advances in understanding SE pathophysiology and new treatment options improve patient outcomes.

Keywords:
ConvulsionsElectrographic statusRefractory status epilepticusSeizuresStatus epilepticus

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Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
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Area of Science:

  • Neurology
  • Emergency Medicine

Background:

  • Status epilepticus (SE) is a prolonged or recurrent seizure event.
  • It necessitates immediate medical intervention to prevent neurological damage.

Purpose of the Study:

  • To review the current understanding of SE pathophysiology.
  • To discuss updated definitions and emerging treatment strategies for SE.

Main Methods:

  • Literature review of recent studies on SE management.
  • Analysis of new data on alternative anti-seizure agents.
  • Evaluation of the role of continuous electroencephalogram (cEEG) monitoring.

Main Results:

  • Improved understanding has refined SE definitions.
  • New data support the safety and efficacy of alternative SE treatments.
  • Wider use of cEEG reveals a higher prevalence of subclinical seizures.

Conclusions:

  • Prompt recognition and treatment of SE are critical.
  • Evolving treatment paradigms offer improved patient management.
  • Subclinical seizures are more common than previously recognized, highlighting the importance of advanced monitoring.