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Development of one paediatric and one neonatal formulary list in hospital settings

Sissel Sundell Haslund-Krog1, Hanne Rolighed Christensen1, Mia Bjerager2

  • 1Department of Clinical Pharmacology, Bispebjerg Hospital, 2400, Copenhagen, Denmark.

British Journal of Clinical Pharmacology
|October 1, 2017
PubMed

Insights

This study outlines the creation of pediatric and neonatal drug formularies for hospital use. The process involved establishing an editorial board, managing drug data, and developing the lists, though it is time-consuming due to data limitations.

Area of Science:

  • Pharmacology
  • Hospital Pharmacy
  • Drug Management

Background:

  • Developing specialized drug formularies for pediatric and neonatal populations is crucial for safe and effective hospital care.
  • Existing drug formularies often lack comprehensive coverage for these vulnerable patient groups.

Purpose of the Study:

  • To describe the systematic process for creating distinct pediatric and neonatal drug formulary lists.
  • To detail the methodology for establishing and maintaining these specialized formularies within a hospital setting.

Main Methods:

  • Organizing an editorial board and establishing a pediatric sub-committee.
  • Procuring and managing drug consumption data, including labeling status, dosing, adverse events, guidelines, evidence, and pricing.
  • Developing the initial editions of the formulary list and manual.

Main Results:

  • The pediatric formulary included 263 out of 1097 evaluated item numbers, with 88% licensed for children.
  • The neonatal formulary included 104 out of 348 evaluated item numbers, with 48% licensed for neonates.
  • Significant proportions of included drugs were unlicensed or extemporaneous preparations, particularly for neonates.

Conclusions:

  • The development of pediatric and neonatal formularies is a complex and time-consuming process.
  • Differences in drug availability, licensing, and age-appropriate formulations present challenges.
  • Standardized processes can facilitate the creation of these essential formularies across different healthcare settings.
Abstract

Keywords:
essential medicinesexcipientsformularyneonatespaediatric

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