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Left Lung Orthotopic Transplantation in a Juvenile Porcine Model for ESLP
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Pediatric lung transplantation.

Roosevelt Bryant1, David Morales1, Marc Schecter2

  • 1Division of Cardiovascular Surgery, The Heart Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, MLC 2004, Cincinnati, Ohio 45229.

Seminars in Pediatric Surgery
|October 2, 2017
PubMed
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Pediatric lung transplantation is a complex procedure with over 2200 cases reported. This review covers transplant history, indications, surgical techniques, and outcomes for children.

Area of Science:

  • Cardiology and Thoracic Surgery
  • Pediatric Pulmonology

Background:

  • Pediatric lung transplantation is a rare and complex procedure, with just over 2200 implants recorded globally since the late 1980s.
  • The International Society for Heart and Lung Transplantation registry provides the primary data source for these rare events.

Purpose of the Study:

  • To provide a comprehensive overview of pediatric lung transplantation.
  • To detail the historical evolution, current indications, and referral processes for pediatric lung transplant candidates.
  • To discuss lung assist devices, surgical techniques, post-transplant outcomes, and retransplantation in pediatric recipients.

Main Methods:

  • This review synthesizes information from the International Society for Heart and Lung Transplantation registry and existing literature.
Keywords:
Cystic fibrosisECMOLungPediatricRespiratory failureTransplant

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  • It covers historical data, clinical indications, patient management strategies, and surgical considerations.
  • Outcomes, morbidity, and retransplantation data are analyzed.

    • Main Results:

    • Over 2200 pediatric lung transplants have been performed globally.
    • The review outlines current criteria for listing pediatric patients for lung transplantation.
    • It details the role of mechanical circulatory support as a bridge to transplant and discusses post-operative outcomes.

    Conclusions:

    • Pediatric lung transplantation has evolved significantly, offering a life-saving option for specific conditions.
    • Understanding the indications, surgical nuances, and long-term outcomes is crucial for successful management.
    • Retransplantation remains an option for select patients facing graft failure.