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Updated: Feb 22, 2026

Small Bowel Transplantation In Mice

Small Bowel Transplantation In Mice

Published on: August 20, 2007

Pediatric intestinal transplantation.

Kyle A Soltys¹, Geoff Bond¹, Rakesh Sindhi¹

¹The Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, 4401 Penn Ave, 6 FP, Pittsburgh, PA 15224.

Seminars in Pediatric Surgery

|October 2, 2017

Summary

This summary is machine-generated.

Intestinal transplantation offers a life-saving option for children with intestinal failure. Advances in surgical techniques and immunosuppression have improved long-term survival and quality of life for these patients.

Keywords:

Immunosuppression Infection Intestinal failure Intestinal transplant Post-transplant lymphoproliferative disease Quality of life

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Published on: November 6, 2012

Tissue Engineering of the Intestine in a Murine Model

Tissue Engineering of the Intestine in a Murine Model

Published on: December 1, 2012

Area of Science:

Gastroenterology and Hepatology
Pediatric Surgery
Transplantation Medicine

Background:

Intestinal transplantation has evolved significantly over the past 30 years.
Improvements in surgical techniques, donor assessment, and immunosuppression have enhanced outcomes.
Intestinal failure in children presents life-threatening complications, necessitating advanced treatment options.

Purpose of the Study:

To review the historical development of intestinal transplantation.
To discuss current pre-operative indications and the success of intestinal rehabilitation.
To analyze the evolution of immunosuppressive strategies and post-transplant complications.

Main Methods:

Literature review focusing on historical developments, indications, rehabilitation, immunosuppression, and outcomes.
Analysis of current research on infectious complications and quality of life.
Synthesis of data on long- and short-term results in pediatric intestinal transplant recipients.

Main Results:

Intestinal transplantation has become a viable option for children with complex intestinal failure.
Intestinal rehabilitation has shown considerable success in managing intestinal failure.
Evolving immunosuppressive protocols aim to mitigate infectious complications and improve long-term survival.

Conclusions:

Pediatric intestinal transplantation offers a chance for long-term survival for children with life-threatening intestinal failure.
Continued advancements in surgical and medical management are crucial for improving patient outcomes.
Further research into quality of life and long-term complications is essential for this patient population.