Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

5.2K
Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
5.2K
Male Sexual Response: Erection & Ejaculation01:17

Male Sexual Response: Erection & Ejaculation

22.8K
Sexual stimulation can take various forms, such as physical touch and visual or auditory cues. When this happens, the parasympathetic reflex in the sacral portion of the spinal cord is activated. This reflex stimulates the release of nitric oxide (NO), which then dilates the arterioles in the penis, increasing blood flow to the erectile tissues - the corpora cavernosa and corpus spongiosum.
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
22.8K
Urinary Tract Calculi VI: Surgical Management01:25

Urinary Tract Calculi VI: Surgical Management

625
Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
625
Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors01:28

Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors

646
Phosphodiesterase 5 (PDE5) inhibitors are potent enzymes that function to hydrolyze cyclic nucleotides to their corresponding 5' monophosphates. Their unique biochemical properties have been applied in treating Pulmonary Arterial Hypertension (PAH).
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
646

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Venous thromboembolism after penile cancer surgery: a UK PeCaN study.

BJU international·2026
Same author

Response to: 'Indirect evidence and cautious sequencing in indeterminate testicular lesions'.

BJU international·2026
Same author

Combination therapy for acute Peyronie' s disease: a success story of translation from bench to bedside.

Nature reviews. Urology·2026
Same author

Author Correction: An update on mechanisms and treatment options for priapism.

Nature reviews. Urology·2026
Same author

Cosmetic Penile Enhancement Surgery and the Role of the Reconstructive Urologist.

European urology focus·2026
Same author

Plaque incision and grafting for peyronie's disease: 15-year experience and functional outcomes from a high-volume andrology centre.

International journal of impotence research·2026
Same journal

Effective Mentorship in Urology Fellowship Training: Qualities, Models, and Equity.

Current urology reports·2026
Same journal

Management of Lower Urinary Tract Symptoms in Patients With Multiple Sclerosis.

Current urology reports·2026
Same journal

Lower Urinary Tract Symptoms as an Indicator of Occult Neurologic Disease: A System-first Framework for Urologic Practice.

Current urology reports·2026
Same journal

Association Between Ambient Temperature and Urolithiasis: A Systematic Review and Meta-analysis.

Current urology reports·2026
Same journal

Is Open Partial Nephrectomy Still an Option in the Robotic Era?

Current urology reports·2026
Same journal

Artificial Intelligence in Urologic Documentation: A Review of Emerging Capabilities and the Ongoing Need for Human Oversight.

Current urology reports·2026
See all related articles

Related Experiment Video

Updated: Feb 22, 2026

Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease
02:21

Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease

Published on: March 15, 2024

1.7K

Surgical Techniques for Managing Post-prostatectomy Erectile Dysfunction.

Fabio Castiglione1, David J Ralph1, Asif Muneer2,3

  • 1Department of Andrology, University College London Hospital, 250 Euston Road, London, NW1 2PG, UK.

Current Urology Reports
|October 2, 2017
PubMed
Summary
This summary is machine-generated.

Radical prostatectomy can cause erectile dysfunction (ED). Nerve-sparing surgery and penile prostheses are effective surgical options for managing post-prostatectomy ED, offering the highest patient satisfaction rates.

Keywords:
Erectile function after radical prostatectomyNerve-sparing radical prostatectomyRadical prostatectomy outcome

More Related Videos

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
09:49

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy

Published on: December 28, 2021

3.9K
Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy
03:25

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy

Published on: June 16, 2022

1.4K

Related Experiment Videos

Last Updated: Feb 22, 2026

Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease
02:21

Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease

Published on: March 15, 2024

1.7K
Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy
09:49

Isolation of Adipose Derived Regenerative Cells for the Treatment of Erectile Dysfunction Following Radical Prostatectomy

Published on: December 28, 2021

3.9K
Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy
03:25

Transcorporal Artificial Urinary Sphincter Cuff Placement in a Case Requiring Revision for Urethral Atrophy

Published on: June 16, 2022

1.4K

Area of Science:

  • Urology
  • Andrology
  • Surgical Oncology

Background:

  • Radical prostatectomy (RP) for prostate cancer increasingly leads to post-operative erectile dysfunction (ED).
  • Understanding pelvic anatomy and neurovascular bundles has improved surgical techniques.
  • Preserving erectile function (EF) is a key goal in modern RP.

Purpose of the Study:

  • To review current literature on surgical management of post-prostatectomy ED.
  • To identify effective surgical interventions for restoring erectile function after RP.

Main Methods:

  • Literature search of PubMed for English-language articles up to Jan 2017.
  • Included studies on "prostatectomy AND erectile dysfunction", "penile prostheses", and "penile implants".
  • Excluded studies evaluating medical treatments.

Main Results:

  • Nerve-sparing RP techniques aim to preserve EF by focusing on vascular supply and neurovascular bundles.
  • Penile prosthesis implantation is a third-line treatment for RP ED, showing high success and patient satisfaction.
  • Nerve-sparing surgery and penile prostheses are definitive methods for preserving erectile function post-RP.

Conclusions:

  • Surgical techniques have evolved to better preserve erectile function after radical prostatectomy.
  • Penile prostheses offer a highly effective solution for patients with persistent post-prostatectomy ED.
  • Nerve-sparing surgery and penile implants are the primary surgical strategies for definitive erectile function restoration.