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Aerobic physical training does not condition against strenuous exercise-induced changes in immune function but
Pablo J Patiño1, Domingo I Caraballo2, Katarzyna Szewczyk3
1Group of Primary Immunodeficiencies, School of Medicine, University of Antioquia, Medellín, Colombia.
The Journal of Sports Medicine and Physical Fitness
|October 3, 2017
Summary
Aerobic physical training (APT) modulates T cell proliferation but does not prevent immune changes from strenuous exercise. Trained individuals showed reduced T cell proliferation compared to sedentary controls post-exercise.
Area of Science:
- Immunology
- Exercise Physiology
- Sports Science
Background:
- Exercise-induced stress significantly impacts the immune system.
- Understanding immune responses to acute and chronic physical stress is crucial.
Purpose of the Study:
- To investigate the effects of aerobic physical training (APT) on immune system parameters.
- To analyze immune changes during acute and chronic physical stress.
Main Methods:
- Untrained males (18-25 years) underwent 6 months of APT or remained sedentary.
- Cardiopulmonary exercise tests (CET) were performed at 0, 3, and 6 months.
- Evaluated B cells, T cells, NK cells, T cell proliferation, and cytokine production pre- and post-CET.
Main Results:
- Both groups showed increased CD4+ T cells and NK cells, and reduced T cell proliferation post-CET.
- Trained individuals exhibited significantly lower resting T cell proliferation than controls.
- No significant differences in cytokine production were observed between groups post-CET.
Conclusions:
- APT does not prevent strenuous exercise-induced immune alterations.
- APT significantly modulates T cell proliferative responses to exercise.
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