Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

7.1K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
7.1K
Multi-species Conserved Sequences02:51

Multi-species Conserved Sequences

4.9K
Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale  studies have provided new insights into the evolutionary relationship between organisms.
Although the genome of each species varies greatly from each other, a few sequences are highly conserved. Such conserved...
4.9K
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

753
Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
753

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

InfoCD: A Contrastive Chamfer Distance Loss for Point Cloud Completion.

Advances in neural information processing systems·2026
Same author

From benchmarking alignment of genome assemblies to IMGT annotation: the paradigm of the bovine Bos taurus T cell receptor (TRG) locus.

BMC genomics·2025
Same author

Effect of Cumulative Exposure on the Efficacy of Paroxetine: A Population Pharmacokinetic-Pharmacodynamic and Machine Learning Analyses.

CPT: pharmacometrics & systems pharmacology·2025
Same author

A nuclear genome assembly of an extinct flightless bird, the little bush moa.

Science advances·2024
Same author

Bacterial induction of B cell senescence promotes age-related changes in the gut microbiota.

Nature cell biology·2023
Same author

Serum Fatty Acid Composition Balance by Fuzzy C-Means Method in Individuals with or without Metabolic Dysfunction-Associated Fatty Liver Disease.

Nutrients·2023
Same journal

Literature-informed gene extraction and ranking for multimodal data fusion.

Briefings in bioinformatics·2026
Same journal

SA-MTP: a structure-aware framework for multifunctional therapeutic peptide annotation.

Briefings in bioinformatics·2026
Same journal

Genome assemblies and annotations are not static and need support for tracking their evolution.

Briefings in bioinformatics·2026
Same journal

A historical journey of metabolite-protein interaction discovery: from data harmonization to AI-driven prediction.

Briefings in bioinformatics·2026
Same journal

Bridging local-global transmembrane protein contexts with contrastive pretraining for alignment-free pathogenicity prediction.

Briefings in bioinformatics·2026
Same journal

Prediction of drug hypersensitivity by comprehensive modeling of HLA-peptidomes.

Briefings in bioinformatics·2026
See all related articles

Related Experiment Video

Updated: Feb 21, 2026

A Practical Guide to Phylogenetics for Nonexperts
12:00

A Practical Guide to Phylogenetics for Nonexperts

Published on: February 5, 2014

36.2K

MAFFT online service: multiple sequence alignment, interactive sequence choice and visualization.

Kazutaka Katoh, John Rozewicki, Kazunori D Yamada

    Briefings in Bioinformatics
    |October 3, 2017
    PubMed
    Summary
    This summary is machine-generated.

    The MAFFT online service now offers enhanced features for large-scale multiple sequence alignment (MSA). These updates provide intuitive tools for biologists to manage and refine extensive biological sequence datasets.

    Keywords:
    multiple sequence alignmentphylogenetic treesequence analysis

    More Related Videos

    An Integrated Approach for Microprotein Identification and Sequence Analysis
    09:37

    An Integrated Approach for Microprotein Identification and Sequence Analysis

    Published on: July 12, 2022

    4.0K
    Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
    09:37

    Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

    Published on: August 15, 2019

    10.5K

    Related Experiment Videos

    Last Updated: Feb 21, 2026

    A Practical Guide to Phylogenetics for Nonexperts
    12:00

    A Practical Guide to Phylogenetics for Nonexperts

    Published on: February 5, 2014

    36.2K
    An Integrated Approach for Microprotein Identification and Sequence Analysis
    09:37

    An Integrated Approach for Microprotein Identification and Sequence Analysis

    Published on: July 12, 2022

    4.0K
    Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
    09:37

    Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

    Published on: August 15, 2019

    10.5K

    Area of Science:

    • Bioinformatics
    • Computational Biology
    • Genomics

    Background:

    • Advances in sequencing technologies generate massive biological sequence data.
    • The demand for multiple sequence alignment (MSA) of large datasets is rapidly increasing.
    • Sophisticated algorithms alone are insufficient for extracting biological insights from large datasets.

    Purpose of the Study:

    • To describe new features in the MAFFT online service for handling large-scale MSAs.
    • To introduce intuitive and interactive tools for experimental biologists.
    • To facilitate the refinement of sequence datasets and MSAs.

    Main Methods:

    • Development of MAFFT focusing on large data handling and interactive usability.
    • Explanation of the Web interface for new large data options.
    • Demonstration of interactive usage for refining sequence data and alignments.

    Main Results:

    • MAFFT online service now includes specific features for processing large numbers of biological sequences.
    • The updated service provides an interactive Web interface for users to refine datasets and alignments.
    • Enhanced tools support experimental biologists in managing and analyzing large-scale sequence data.

    Conclusions:

    • The MAFFT online service has been improved with features to address the growing need for large-scale MSA.
    • New interactive tools empower biologists to efficiently manage and refine complex sequence data.
    • These developments enhance the utility of MAFFT for extracting biological information from massive sequencing outputs.