Related Experiment Video
Updated: Feb 21, 2026
Author Spotlight: Assessing the Cardiovascular Profile of Patients with Metabolic Syndrome
Published on: September 27, 2024
Hypertension, C Reactive Protein and Metabolic Profile: What is the Scenario in Patients Undergoing Arteriography?
Ricardo Jose Tofano1, Sandra Maria Barbalho2, Marcelo Dib Bechara3
1Cardiologist, Cardiac Surgery Unit and Hemodynamics, Medical School of Marilia, Marilia, Sao Paulo, Brazil.
Insights
High blood pressure (HBP) is linked to higher risks of diabetes, metabolic syndrome, and cardiovascular disease. Controlling HBP is crucial for better health outcomes and longevity.
Area of Science:
- Cardiology
- Endocrinology
- Metabolic Health
Background:
- High Blood Pressure (HBP), Diabetes Mellitus (DM), Metabolic Syndrome (MS), and Cardiovascular Diseases (CVD) are leading causes of mortality globally.
- HBP is a prevalent chronic condition and a significant, modifiable risk factor for vascular events and mortality.
Purpose of the Study:
- To investigate the association between high-sensitivity C-reactive protein (hs-CRP) levels and biochemical/anthropometric profiles in hypertensive and non-hypertensive patients undergoing arteriography.
- To identify risk factors associated with HBP in patients undergoing arteriography.
Main Methods:
- Ninety-five patients undergoing arteriography were assessed for anthropometric (BMI, waist circumference) and biochemical parameters (glycaemia, lipids, hs-CRP).
- Blood pressure, atherogenic indices, MS diagnosis, and catheterization details were collected.
- Statistical analyses included Chi-square, Fisher, Student t-test, and ANOVA with Tukey's test.
Main Results:
- 78.95% of patients had HBP. Hypertensive individuals exhibited significantly higher glycaemia (indicating DM), triglycerides, waist circumference, BMI, and hs-CRP levels.
- Over 93% of hypertensive patients had MS, correlating with more severe arterial lesions and increased need for invasive procedures like angioplasty and surgery.
Conclusions:
- Blood pressure control is essential for improving quality of life and life expectancy.
- HBP is associated with multiple risk factors that elevate morbidity and mortality, underscoring the need for effective management.
Introduction:
High Blood Pressure (HBP), Diabetes Mellitus (DM), Metabolic Syndrome (MS) and Cardiovascular Diseases (CVD) are among the main causes of death worldwide and HBP is one of the most common chronic health problem representing an important and modifiable risk factor for vascular events and mortality.
Aim:
To study the association among high sensitivity CRP levels, and the biochemical, and anthropometric profile in hypertensive and non-hypertensive patients who underwent arteriography.
Materials And Methods:
This research was performed at the Haemodynamic Laboratory of the University Hospital in the city of Marilia - state of São Paulo, Brazil. Ninety-five subjects who underwent arteriography were included. Anthropometric (body mass index and waist circumference) and biochemical parameters (glycaemia, total cholesterol, HDL-c, LDL-c, triglycerides, and high sensitivity C reactive protein), were evaluated. Variables pertaining to blood pressure, atherogenic indices, diagnosis of metabolic syndrome and catheterization details were collected. Statistical analysis was performed with Chi-square test, Fisher, Student t-test and ANOVA complemented by Tukey test.
Results:
Our results showed that 78.95% of the patients who underwent arteriography were suffering from HBP. Hypertensive individuals had significantly higher glycaemia (124.14±45.33 mg/dL) or DM, higher values of triglycerides (195.27±74.52 mg/dL), waist circumference (98.52±12.52 cm), body mass index (29.99±1.41 kg/m2) and hs-CRP (0.53±0.44 mg/dL). Most of the hypertensive patients (93.33%) presented with MS and were related to the presence of more severe lesions in the arteries and had passed through more invasive procedures like angioplasty and surgery.
Conclusion:
Our findings indicate that blood pressure control is of paramount importance to ensure better quality of life and life expectancy as it is associated with several risk factors that increase the morbidity and mortality.
More Related Videos
10:03Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
Published on: January 28, 2020
13:45A Method to Study the Correlation Between Local Collagen Structure and Mechanical Properties of Atherosclerotic Plaque Fibrous Tissue
Published on: November 11, 2022
Related Concept Videos
01:19Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
01:27Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
01:30Acute Coronary Syndrome III: Diagnostic Studies
01:25Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
01:30Coronary Artery Disease I: Introduction
01:20Blood Studies for Cardiovascular System I: Cardiac Biomarkers
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...