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Theseus, the Labyrinth, and the Minotaur of anaesthetic-induced developmental neurotoxicity

R D Sanders1, D Andropoulos2, D Ma3

  • 1Department of Anesthesiology, Anesthesiology & Critical Care Trials & Interdisciplinary Outcomes Network (ACTION), University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

British Journal of Anaesthesia
|October 4, 2017
PubMed
Abstract

No abstract available in PubMed .

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Local Anesthetics: Adverse Effects01:12

Local Anesthetics: Adverse Effects

While local anesthetics are generally safe and well-tolerated, they can occasionally cause adverse effects that vary in severity. Local anesthetics can induce toxicity at two distinct levels. They can either produce local effects through direct contact with the neural elements or be absorbed into the bloodstream from the injection site, leading to systemic effects.
Once absorbed into the systemic circulation, local anesthetics can affect the organs that depend on the functioning of sodium...
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