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Antipsychotics: how strict the formulary?

B Alexander1

  • 1Department of Pharmacy, Veterans Administration Medical Center, Iowa City, IA.

Drug Intelligence & Clinical Pharmacy
|April 1, 1988
PubMed
Summary
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This study recommends specific antipsychotic medications for formulary inclusion, considering efficacy and patient response. It also provides guidance for managing patients on nonformulary antipsychotic drugs.

Area of Science:

  • Pharmacology
  • Psychiatry
  • Health Services Research

Background:

  • Seventeen antipsychotic medications are currently available in the U.S. formulary.
  • Key considerations for antipsychotic formulary decisions include efficacy, patient response, adverse effects, dosage forms, and generic availability.

Purpose of the Study:

  • To recommend antipsychotic medications for formulary inclusion.
  • To provide guidance on managing patients prescribed nonformulary antipsychotics.

Main Methods:

  • Review of research and clinical considerations for antipsychotic selection.
  • Development of a management strategy for patients on nonformulary antipsychotics.

Main Results:

  • Chlorpromazine, thioridazine, haloperidol, and fluphenazine are recommended for formulary inclusion.

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  • A framework for managing patients on nonformulary antipsychotics is presented.

    • Conclusions:

    • Formulary decisions for antipsychotics should balance efficacy, safety, and practical considerations.
    • Clinical guidelines are essential for optimizing antipsychotic therapy and managing formulary limitations.