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Intractable Blepharospasm Treated with Bilateral Pallidal Deep Brain Stimulation.

Nijee S Luthra1, Kyle T Mitchell1, Monica M Volz1

  • 1Department of Neurology, University of California, San Francisco, CA, USA.

Tremor and Other Hyperkinetic Movements (New York, N.Y.)
|October 5, 2017
PubMed
Summary

Deep brain stimulation (DBS) of the globus pallidus (GP) effectively treated a patient with severe blepharospasm. This neurological intervention provided sustained relief from incapacitating symptoms.

Keywords:
Deep brain stimulationblepharospasmcranial dystoniaglobus pallidus internuspallidal stimulation

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Area of Science:

  • Neurology
  • Neurosurgery
  • Movement Disorders

Background:

  • Blepharospasm is a type of dystonia that can cause significant disability.
  • It may occur alone or with other cranial dystonias.

Observation:

  • A 69-year-old male presented with craniocervical dystonia, primarily severe blepharospasm.
  • His condition was refractory to conventional medical therapies.

Findings:

  • The patient underwent bilateral globus pallidus (GP) deep brain stimulation (DBS).
  • This resulted in complete resolution of blepharospasm with sustained benefits at 12 months.

Implications:

  • This case highlights the efficacy of pallidal stimulation for blepharospasm.
  • GP-DBS is a viable therapeutic option for intractable blepharospasm.