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Updated: Feb 21, 2026

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Normothermic Ex Vivo Kidney Perfusion for the Preservation of Kidney Grafts prior to Transplantation
Published on: July 15, 2015
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Potential yield of imminent death kidney donation
Ryan A Denu1, Eneida A Mendonca2, Norman Fost3
1Department of Medicine, University of Wisconsin, Madison, WI, USA.
Summary
"Imminent death" kidney donation could significantly reduce the national organ waitlist. This living donation strategy may provide a vital opportunity for many more individuals to donate kidneys.
Area of Science:
- Nephrology
- Transplantation
- Bioethics
Background:
- Approximately 99,000 individuals are on the kidney transplant waiting list in the U.S.
- Many patients die while awaiting a kidney transplant.
- Imminent death donation, a form of living donation, is gaining attention.
Purpose of the Study:
- To estimate the number of potential imminent death kidney donors.
- To assess the feasibility of increasing organ availability through end-of-life discussions.
Main Methods:
- Assessed annual deaths of individuals with normal kidney function at a single center.
- Extrapolated findings to national transplant centers.
- Utilized previous survey data on willingness to donate.
Main Results:
- Estimated 76-396 eligible and willing imminent death donors annually in Wisconsin.
- Projected 5,925-31,097 eligible and willing imminent death donors nationally per year.
- Identified a substantial potential increase in kidney donors.
Conclusions:
- Allowing imminent death donation could significantly decrease the kidney waiting list.
- Integrating organ donation conversations into end-of-life planning is crucial.
- This approach offers more opportunities for living kidney donation.
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