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Amniotic Membrane Grafts to Reduce Pterygium Recurrence.
1Department of Ophthalmology, Kaiser Permanente Medical Center, Panorama City, CA.
Cornea
|October 5, 2017
Summary
Pterygium surgery using amniotic membrane transplantation (AMT) and mitomycin C (MMC) shows low recurrence rates. This combined approach offers an effective and efficient surgical option for pterygium management.
Area of Science:
- Ophthalmology
- Surgical Innovation
Background:
- Pterygium is a common ocular condition.
- Recurrence after pterygium excision remains a challenge.
Purpose of the Study:
- To evaluate the long-term outcomes of pterygium surgery.
- To assess the efficacy of adjunctive amniotic membrane transplantation (AMT) and intraoperative mitomycin C (MMC).
Main Methods:
- Retrospective study of 556 eyes from 535 patients.
- Pterygium excision with adjunctive AMT and intraoperative MMC.
- Follow-up of at least 6 months.
Main Results:
- Overall recurrence rate of 5.8% (corneal 3.6%, conjunctival 2.2%).
- Reoperation rate of 2%.
- Low incidence of complications like granuloma and diplopia.
Conclusions:
- Adjunctive AMT and short MMC exposure effectively reduce pterygium recurrence.
- The combined procedure is efficient, leading to early recovery.
- Conjunctiva is preserved for potential future surgeries.

