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Postinfarction left ventricular free wall rupture: a 17-year single-centre experience.
Francesco Formica1, Serena Mariani1, Gurmeet Singh2
1Department of Medicine and Surgery, Cardiac Surgery Clinic, San Gerardo Hospital, University of Milano-Bicocca, Monza, Italy.
Cardiac arrest during acute myocardial infarction significantly increases mortality risk in patients with left ventricular free wall rupture (LVFWR). Prompt diagnosis and surgical intervention are crucial for improving survival rates in this high-risk condition.
Area of Science:
- Cardiology
- Cardiac Surgery
- Critical Care Medicine
Background:
- Left ventricular free wall rupture (LVFWR) is a rare but devastating complication of acute myocardial infarction.
- LVFWR carries a high mortality rate, estimated between 60% and 90% without surgical intervention.
Purpose of the Study:
- To identify risk factors associated with morbidity and mortality in patients experiencing LVFWR.
- To evaluate the long-term outcomes following surgical repair of LVFWR.
Main Methods:
- Retrospective analysis of 35 patients who underwent surgery for LVFWR between 2000 and 2016.
- Univariable and multivariable analyses were performed to identify predictors of in-hospital mortality.
Main Results:
- In-hospital survival was 65.7%.
- Cardiac arrest at presentation was an independent predictor of in-hospital mortality (OR 11.7, P=0.003).
- Five-year and 10-year overall survival rates were 53.2% and 49.1%, respectively.
Conclusions:
- Early diagnosis and prompt surgical intervention are critical for managing LVFWR.
- Patients surviving high-risk LVFWR surgery show a trend towards long-term benefit.
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