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Updated: Feb 21, 2026

High-Efficiency Generation of Antigen-Specific Primary Mouse Cytotoxic T Cells for Functional Testing in an Autoimmune Diabetes Model
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Antigen-Specific Peptide Immunotherapy for Type 1 Diabetes: Proof of Safety, Hope for Efficacy

Ken Coppieters1, Matthias von Herrath2

  • 1Global Research Project Management, Novo Nordisk A/S, Måløv, Denmark.

Cell Metabolism
|October 6, 2017
PubMed

Antigen-specific immunotherapy has long been hailed as the ideal disease-modifying approach for type 1 diabetes, both for disease prevention and reversal. A small phase 1 trial now demonstrates safety of a peptide-based treatment in recently diagnosed adults.

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