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Patch Testing in Patients with Suspected Footwear Dermatitis: A Retrospective Study.
Taru Garg1, Soumya Agarwal1, Shiwangi Rana1
1Department of Dermatology and STD, Lady Hardinge Medical College, New Delhi, India.
Indian Dermatology Online Journal
|October 6, 2017
Summary
Footwear dermatitis is often misdiagnosed. Patch testing identified hydroquinone monobenzylether and 4-aminoazobenzene as common allergens in allergic contact dermatitis to footwear.
Area of Science:
- Dermatology
- Allergology
- Contact Dermatitis
Background:
- Footwear dermatitis is a prevalent but frequently overlooked condition.
- Patch testing is crucial for diagnosing footwear-related allergic contact dermatitis (ACD) and identifying specific allergens.
Purpose of the Study:
- To determine the prevalence of positive patch test reactions in suspected footwear ACD cases.
- To identify the most frequent allergens responsible for footwear-induced ACD.
Main Methods:
- A retrospective study analyzed 37 patients with suspected footwear ACD.
- Patch testing was performed using the Indian standard series and Indian footwear series between July 2012 and July 2015.
Main Results:
- Positive patch tests were observed in 18.92% of patients.
- Hydroquinone monobenzylether (8.11%) and 4-aminoazobenzene (5.41%) were the most common allergens.
- The dorsal aspects of the feet were the most frequently affected sites (81.08%).
Conclusions:
- Rubber, rubber additives, and dyes are common culprits in footwear-related ACD.
- Hydroquinone monobenzylether and 4-aminoazobenzene are principal allergens causing footwear ACD.

