Related Experiment Video
Updated: Feb 21, 2026

Novel Percutaneous Approach for Deployment of 3D Printed Coronary Stenosis Implants in Swine Models of Ischemic Heart Disease
Published on: February 18, 2020
The safety and feasibility of guidezilla catheter in complex coronary interventions and an observational study
Jianying Ma1, Lei Hou, Juying Qian
1Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.
Insights
The Guidezilla guide extension catheter safely and effectively facilitates device delivery during percutaneous coronary intervention for complex coronary anatomy, including chronic total occlusions and tortuous vessels.
Area of Science:
- Interventional Cardiology
- Medical Device Technology
Background:
- Percutaneous coronary intervention (PCI) can be challenging in complex coronary anatomy.
- The Guidezilla guide extension catheter was developed to enhance support and device delivery in such cases.
Purpose of the Study:
- To evaluate the safety and efficacy of the Guidezilla catheter in PCI for complex coronary anatomy.
- To assess target lesion crossing success, procedural success, and complication rates.
Main Methods:
- Retrospective, single-center study of 188 consecutive patients undergoing PCI with the Guidezilla catheter (March 2015 - August 2016).
- Data collected on lesion complexity, target vessel, access site, and procedural outcomes.
Main Results:
- The Guidezilla catheter was most frequently used for chronic total occlusions (45%) and heavy calcification (37%).
- Target lesion crossing and procedural success rates were both 99%.
- A single device-related complication (proximal vessel dissection) occurred and was successfully managed; 90% of procedures were completed via radial access.
Conclusions:
- The Guidezilla guide extension catheter is safe and efficacious for PCI in complex coronary anatomy.
- It significantly facilitates device delivery, particularly when using radial access with experienced operators.
Abstract:
The monorail Guidezilla guide extension catheter was designed to provide additional backup and facilitate device delivery in percutaneous coronary intervention (PCI) for complex coronary anatomy such as chronic total occlusion (CTO), extreme vessel tortuosity, diseased bypass grafts, and anomalous coronary arteries, among others.The present retrospective, single-center study included 188 consecutive patients who underwent PCI using the Guidezilla catheter from March 2015 to August 2016. Study outcomes were rates of target lesion crossing success, procedural success, and complications.The Guidezilla catheter was used most commonly in PCI of CTOs (45%) and heavy proximal calcification (37%), followed by tortuosity (10%), previously deployed proximal stents (4%), and coronary artery anomaly (4%). The right coronary artery (48%) was most commonly intervened followed by the left ascending (35%) and left circumflex (17%) arteries. Rates of target lesion crossing success and procedural success were both 99%, with one device-related periprocedural complication, namely proximal vessel dissection secondary to deep insertion which was successfully treated with stent implantation. Ninety percent of PCI were performed and completed successfully by radial access.In a single center with experienced operators, the use of the Guidezilla guide extension catheter in PCI of complex coronary anatomy performed mostly via radial artery access appeared safe and efficacious, and greatly facilitated device delivery.
Related Concept Videos
Cardiac Catheterization III: Left Heart Catheterization
Cardiac Catheterization I: Pre-Procedure Overview
Cardiac Catheterization IV: Nursing Management
Cardiac Catheterization II: Right Heart Catheterization
Acute Coronary Syndrome III: Diagnostic Studies

