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Updated: Feb 21, 2026

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent
Published on: September 3, 2013
Synthesis and evaluation of MR probes for targeted-reporter imaging
Kirti Dhingra Verma1, Justin O Massing2, Sarah G Kamper2
1Department of Biomedical Engineering , Case Center for Imaging Research , The NFCR Center for Molecular Imaging , Case Western Reserve University , Cleveland , Ohio 44106-7207 , USA.
Abstract:
Visualizing disease heterogeneity remains a challenging task since most imaging agents are targeted to a single receptor. We describe the development of an MR platform able to report on multiple molecular events. Enzyme activation and enhanced cellular uptake of this modular probe make it suitable for subsequent targeted-reporter imaging applications.
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