Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Hypertension: Classification and Pathogenesis01:30

Pulmonary Hypertension: Classification and Pathogenesis

702
Pulmonary hypertension (PH) is a severe health condition in which the mean pulmonary arterial pressure increases to 25 mmHg or more, even when the body is at rest. This high pressure in the blood vessels that transport blood from the heart to the lungs can cause various symptoms, including shortness of breath, can lead to right heart failure, and significantly affect the overall quality of life.
There are various classifications for PH, each relating to different underlying causes and also...
702
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

3.9K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
3.9K
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

935
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
935
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

1.7K
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
1.7K
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

308
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
308
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

4.9K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
4.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transpulmonary bubble transit in patients hospitalised with COVID-19 pneumonia.

BMJ open respiratory research·2025
Same author

Rare but serious: pulmonary vascular disease around the world.

JHLT open·2025
Same author

Tenecteplase With Concomitant Anticoagulation for Acute Respiratory Failure in Patients With COVID-19: A Randomized Controlled Trial.

Cureus·2024
Same author

High-Risk Pulmonary Embolism During Labor: <i>JACC</i> Patient Care Pathways.

JACC. Case reports·2023
Same author

High-Risk Pulmonary Embolism During Labor: JACC Patient Care Pathways.

Journal of the American College of Cardiology·2022
Same author

Pre-hospital antiplatelet medication use on COVID-19 disease severity.

Heart & lung : the journal of critical care·2021

Related Experiment Video

Updated: Feb 21, 2026

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
08:34

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat

Published on: November 18, 2018

7.7K

Pulmonary Vascular Diseases in the Elderly.

Hooman Poor1

  • 1Division of Pulmonary, Critical Care, and Sleep Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1232, New York, NY 10029, USA.

Clinics in Geriatric Medicine
|October 10, 2017
PubMed
Summary

Pulmonary hypertension is a hemodynamic condition affecting older adults due to aging and comorbidities. Diagnosis requires right heart catheterization, with treatment focusing on underlying causes and pulmonary vasodilators for pulmonary arterial hypertension.

Keywords:
ElderlyPulmonary arterial hypertensionPulmonary hypertensionPulmonary vascular disease

More Related Videos

A Model of Reverse Vascular Remodeling in Pulmonary Hypertension Due to Left Heart Disease by Aortic Debanding in Rats
07:41

A Model of Reverse Vascular Remodeling in Pulmonary Hypertension Due to Left Heart Disease by Aortic Debanding in Rats

Published on: March 1, 2022

3.5K
Characterization of the Isolated, Ventilated, and Instrumented Mouse Lung Perfused with Pulsatile Flow
10:02

Characterization of the Isolated, Ventilated, and Instrumented Mouse Lung Perfused with Pulsatile Flow

Published on: April 29, 2011

16.9K

Related Experiment Videos

Last Updated: Feb 21, 2026

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
08:34

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat

Published on: November 18, 2018

7.7K
A Model of Reverse Vascular Remodeling in Pulmonary Hypertension Due to Left Heart Disease by Aortic Debanding in Rats
07:41

A Model of Reverse Vascular Remodeling in Pulmonary Hypertension Due to Left Heart Disease by Aortic Debanding in Rats

Published on: March 1, 2022

3.5K
Characterization of the Isolated, Ventilated, and Instrumented Mouse Lung Perfused with Pulsatile Flow
10:02

Characterization of the Isolated, Ventilated, and Instrumented Mouse Lung Perfused with Pulsatile Flow

Published on: April 29, 2011

16.9K

Area of Science:

  • Cardiology
  • Pulmonology
  • Geriatrics

Background:

  • Pulmonary hypertension is a hemodynamic condition defined by elevated pulmonary arterial pressure.
  • Aging leads to cardiac and vascular stiffening, increasing pulmonary hypertension risk in the elderly.
  • Comorbidities common in older adults contribute to pulmonary hypertension development.

Purpose of the Study:

  • To define pulmonary hypertension and its increased prevalence in the elderly.
  • To outline diagnostic methods for pulmonary hypertension.
  • To summarize general and specific treatment strategies for pulmonary hypertension.

Main Methods:

  • Definition of pulmonary hypertension based on mean pulmonary arterial pressure.
  • Identification of risk factors associated with aging and comorbidities.
  • Description of diagnostic procedures, specifically right heart catheterization.
  • Overview of therapeutic approaches.

Main Results:

  • Pulmonary hypertension is diagnosed when mean pulmonary arterial pressure is ≥25 mm Hg at rest.
  • Age-associated changes and comorbidities increase pulmonary hypertension prevalence in elderly patients.
  • Right heart catheterization is essential for diagnosis and characterization.
  • Treatment involves addressing underlying conditions and using pulmonary vasodilators for pulmonary arterial hypertension.

Conclusions:

  • Pulmonary hypertension is increasingly prevalent in the elderly due to physiological aging and comorbidities.
  • Accurate diagnosis relies on right heart catheterization.
  • Management strategies should target underlying causes, with pulmonary vasodilators indicated for pulmonary arterial hypertension.