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Methods for Quantitative Detection of Antibody-induced Complement Activation on Red Blood Cells
Published on: January 29, 2014
Serum complement levels in normal pregnancy and pregnancy-induced hypertension
1Food & Drug Toxicology Research Centre, National Institute of Nutrition, Jamai-osmania, Hyderabad, India.
Serum complement assay (CH50) was carried out in urban low-income women belonging to the following groups: (i) non-pregnant and non-lactating women; (ii) pregnant women in different periods of gestation; (iii) women suffering from pregnancy-induced hypertension. Serum CH50 titers showed significant increase in the second and third trimester pregnancies as compared to non-pregnant, non-lactating women. There were no differences in CH50 levels between women suffering from pregnancy-induced hypertension and those with normal pregnancy of comparable period of gestation. Nutritional status did not seem to have any influence on complement titers.
Serum complement assay (CH50) was carried out in urban low-income women belonging to the following groups: (i) non-pregnant and non-lactating women; (ii) pregnant women in different periods of gestation; (iii) women suffering from pregnancy-induced hypertension. Serum CH50 titers showed significant increase in the second and third trimester pregnancies as compared to non-pregnant, non-lactating women. There were no differences in CH50 levels between women suffering from pregnancy-induced hypertension and those with normal pregnancy of comparable period of gestation. Nutritional status did not seem to have any influence on complement titers.
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