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Immunocytochemical study of S-100 protein in human pituitary adenomas
G Turpin1, H M Heshmati, M Kujas
1Department of Endocrinology, Hôpital de la Pitié, Paris, France.
Abstract:
The S-100 protein was localized by immunocytochemistry in 70 pituitary tumors including 30 prolactin, 16 growth hormone, two corticotropin and 22 non-functioning adenomas. Positive immunostaining was observed in only one case (prolactin adenoma). It is concluded that in functioning and non-functioning pituitary tumors there is no particular involvement of S-100 protein-containing cells, at least under the conditions of this study.