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Laryngeal chondroradionecrosis following radiotherapy
Giulianno Molina Melo1,2, Paula Demetrio Souza1,2, Luiz Castro Bastos1
1Universidade Federal de São Paulo, Disciplina de Cirurgia de Cabeça e Pescoço, Departamento de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, São Paulo, SP, Brasil.
Objective:
to study larynx chondroradionecrosis related to radiotherapy and chemotherapy treatment and provide a treatment flowchart.
Methods:
retrospective study with clinical data analysis of all larynx cancer patients admitted in a two tertiary hospital in a five years period.
Results:
from 131 patients treated for larynx cancer, 28 underwent chemoradiotherapy with curative intent and three of them presented chondroradionecrosis. They were treated with hiperbaric oxigen therapy and surgical debridment following our flowchart, preserving the larynx in all.
Conclusions:
the incidence of chondroradionecrosis as a complication of chemoradiotherapy in our series was 10,7% and the treatment with hiperbaric oxigen therapy, based in our flowchart, was effective to control this complication.
