Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

1.5K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Defining a standards framework for ophthalmology real-world data methodologies through an expert-led Delphi consensus.

Eye (London, England)·2026
Same author

AI-Assisted OCT Clinical Phenotypes of Diabetic Macular Edema: A Large Cohort Clustering Study.

Journal of clinical medicine·2025
Same author

Complexities in the Terminology Used for Describing, Diagnosing, and Classifying Retinal Vasculitis: A Scoping Review from the International Uveitis Study Group (IUSG) Retinal Vasculitis Study (ReViSe)-Report 6.

Ocular immunology and inflammation·2025
Same author

Minimum set of outcome measures for non-advanced age-related macular degeneration: a Delphi consensus statement by the TRACER (intermediate age-related macular degeneration) study group.

The British journal of ophthalmology·2025
Same author

Ten-Year Incidence, Risk Factors and Progression Rate of Macular Atrophy in Neovascular Age-Related Macular Degeneration.

Clinical & experimental ophthalmology·2025
Same author

Progression of Loss of Vision From Centre-Involving Macular Atrophy in Eyes Treated for nAMD.

Clinical & experimental ophthalmology·2025
Same journal

Pseudo-Choroidal Melanocytosis in Birdshot Chorioretinitis: A Case Series from a Prospective Cohort.

Ocular immunology and inflammation·2026
Same journal

Clinically Suspected Choroidal Lymphoma Arising from Indolent Nonprogressive Multifocal Choroidal Lesions: A Case Report and Literature Review.

Ocular immunology and inflammation·2026
Same journal

Multimodal Imaging of Choroidal Lymphoma: Diagnostic Features, Differential Diagnosis, and Clinical Monitoring.

Ocular immunology and inflammation·2026
Same journal

Presumed Bilateral Retinitis Associated with JC Virus in a Patient with HIV AIDS.

Ocular immunology and inflammation·2026
Same journal

Safety and Efficacy of Adalimumab in the Treatment of Refractory Behçet's Uveitis: A Prospective Cohort Study.

Ocular immunology and inflammation·2026
Same journal

Role of Adjunctive Intravitreal Therapy in Intraocular Tubercular Granuloma at a Tertiary Uveitis Care Centre - A Retrospective Case Series.

Ocular immunology and inflammation·2026
See all related articles

Related Experiment Video

Updated: Feb 21, 2026

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
03:47

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography

Published on: November 1, 2024

424

Choroidal Structural Changes in Tubercular Multifocal Serpiginoid Choroiditis.

Aniruddha Agarwal1, Rupesh Agrawal2,3,4, Neha Khandelwal2

  • 1a Advanced Eye Center, Post Graduate Institute of Medical Education and Research , Chandigarh , India.

Ocular Immunology and Inflammation
|October 12, 2017
PubMed
Summary
This summary is machine-generated.

This study reveals that choroidal vascularity index (CVI) changes in patients with tubercular multifocal serpiginoid choroiditis (TB MSC). Active TB MSC shows decreased CVI, which remodels as lesions heal, indicating structural changes in the choroid.

More Related Videos

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

4.3K
Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography
03:35

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography

Published on: December 1, 2023

784

Related Experiment Videos

Last Updated: Feb 21, 2026

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
03:47

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography

Published on: November 1, 2024

424
Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
10:14

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

4.3K
Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography
03:35

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography

Published on: December 1, 2023

784

Area of Science:

  • Ophthalmology
  • Immunology
  • Infectious Diseases

Background:

  • Tubercular multifocal serpiginoid choroiditis (TB MSC) is an inflammatory eye condition.
  • Understanding choroidal vascular changes in TB MSC is crucial for disease management.

Purpose of the Study:

  • To evaluate choroidal vascular changes in TB MSC patients using enhanced-depth imaging optical coherence tomography (EDI-OCT).
  • To quantify the choroidal vascularity index (CVI) in TB MSC and compare it with healthy controls.

Main Methods:

  • EDI-OCT imaging was performed on 18 TB MSC patients and 30 healthy controls.
  • Image analysis involved segmentation to derive choroidal area, luminal area, stromal area, and CVI.

Main Results:

  • TB MSC patients exhibited a significantly lower CVI (65.46% ± 2.53%) compared to controls (66.90% ± 1.77%).
  • A significant reduction in CVI was observed at 3-month follow-up (63.77% ± 3.91%).
  • Choroidal thickness was significantly higher in TB MSC patients (329.33 µm ± 27.69 µm) than in controls (278.90 µm ± 57.84 µm).

Conclusions:

  • CVI is a valuable metric for assessing choroidal structural alterations in TB MSC.
  • Active TB MSC is associated with reduced choroidal vascularity.
  • Choroidal remodeling and choriocapillaris atrophy occur during lesion healing in TB MSC.