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Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023
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The MMPI and closed-head injury
Dennis P Alfano1, Patricia M Neilson1, Christopher E Paniak2
1a Department of Psychology , University of Regina.
The Clinical Neuropsychologist
|October 13, 2017
Summary
This study on closed-head injury patients found differences in Minnesota Multiphasic Personality Inventory profiles between males and females. The D scale was a common high-point for both, but specific configurations varied by sex.
Area of Science:
- Neuropsychology
- Psychological assessment
Background:
- Closed-head injury (CHI) can lead to significant cognitive and emotional deficits.
- Understanding psychological sequelae is crucial for effective patient management.
- The Minnesota Multiphasic Personality Inventory (MMPI) is a widely used tool for assessing psychopathology.
Purpose of the Study:
- To investigate differences in MMPI profile configurations between males and females with CHI.
- To identify specific MMPI scales and code types that characterize male and female CHI populations.
Main Methods:
- Matched samples of males (n=77) and females (n=25) with CHI were analyzed.
- Minnesota Multiphasic Personality Inventory (MMPI) profile configurations were examined.
- Statistical comparisons were made for scale elevations and two-point code types.
Main Results:
- Male high-point: 5c scale; Female high-point: D scale.
- Male two-point code: 8-2 configuration; Female two-point code: 2-3 configuration.
- Males scored significantly higher on the Sc scale; D scale was most frequent high-point for both sexes.
Conclusions:
- Distinct MMPI profile patterns exist between males and females following closed-head injury.
- The D scale is a prevalent indicator in both groups, but sex-specific configurations (e.g., Hs and Hy for females) are noted.
- Highlights the importance of considering sex differences and methodological rigor in neuropsychological research and clinical practice.

