Related Experiment Video
Updated: Feb 21, 2026

Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Published on: January 20, 2023
The MMPI and closed-head injury
Dennis P Alfano1, Patricia M Neilson1, Christopher E Paniak2
1a Department of Psychology , University of Regina.
Abstract:
This study examined Minnesota Multiphasic Personality Inventory profile configuration in matched samples of males (n = 77) and females (n = 25) suffering from closed-head injury. For the males, the mean group high-point was the 5c scale; the mean group high-point for the females was the D scale. For the males, the mean group two-point code was the 8-2 configuration; the mean group two-point code for the females was the 2-3 configuration. The males as a group also scored significantly higher than the females on the Sc scale. The D scale was the most frequently elevated clinical scale and high-point for both groups. The overall pattern of findings also suggested a greater predominance of Hs and Hy two-point code types for the females. The results are discussed in terms of the need to pay critical attention to methodological issues in neuropsychological research and practice.

