Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pleural Effusion II: Symptoms and Management01:28

Pleural Effusion II: Symptoms and Management

859
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
859
Pleural Effusion I: Introduction01:25

Pleural Effusion I: Introduction

4.7K
Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
4.7K
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

3.3K
The pathophysiology of pneumonia involves the following steps:
3.3K
Other Pulmonary Disorders01:17

Other Pulmonary Disorders

1.7K
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
1.7K
Pleural Disorders: Types and Brief Description01:30

Pleural Disorders: Types and Brief Description

748
The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
748
Pericarditis II: Clinical Features and Diagnostic Tests01:19

Pericarditis II: Clinical Features and Diagnostic Tests

389
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
389

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Shape-Sensing Robotic Bronchoscopy with Integrated Mobile Cone-Beam CT Guidance for Intraoperative Localization of Lung Tumors Using Indocyanine Green.

Diagnostics (Basel, Switzerland)·2026
Same author

Lymph Node Sampling Patterns and Completeness of Staging During Systematic Mediastinal Lymph Node Staging in Patients with Locally Advanced Non-Small-Cell Lung Cancer: A Post Hoc Analysis from the SEISMIC Study.

Cancers·2026
Same author

Ultrasound imaging features of cervical lymph nodes with melanoma metastasis compared with benign cervical nodes.

Melanoma research·2026
Same author

Diagnostic evaluation of pleural effusion in patients with non-small lung cancer affects time to diagnosis and treatment initiation.

Journal of thoracic disease·2026
Same author

HSR26-231: Diagnostic Performance of the Bexa™ Breast Exam for Detection of Breast Masses: A Prospective Single-Center Study.

Journal of the National Comprehensive Cancer Network : JNCCN·2026
Same author

The evolving role of interventional pulmonology with endobronchial ultrasonography in the diagnosis of lymphoma: a narrative review.

Mediastinum (Hong Kong, China)·2026
Same journal

Contemporary Concise Review 2025: Asthma.

Respirology (Carlton, Vic.)·2026
Same journal

Early Intervention With Biologics for Asthma Remission: Promising or Premature?

Respirology (Carlton, Vic.)·2026
Same journal

Clinical and Inflammatory Phenotypes During Exacerbations Predict In-Hospital Adverse Outcomes in Asthma-COPD Overlap.

Respirology (Carlton, Vic.)·2026
Same journal

Diagnostic Yield of EBUS Mediastinal Cryobiopsy Versus TBNA in Suspected Lymphoproliferative Disorders: A Prospective Multicentre Study.

Respirology (Carlton, Vic.)·2026
Same journal

Association of Airway Mucus Plugs and Physical Activity, Exercise Tolerance, Sarcopenia, and Frailty in Patients With COPD and Pre-COPD.

Respirology (Carlton, Vic.)·2026
Same journal

An Age-Friendly Approach to Caring for Chronic Lung Disease in the Ambulatory Setting.

Respirology (Carlton, Vic.)·2026
See all related articles

Related Experiment Video

Updated: Feb 21, 2026

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
07:54

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice

Published on: December 21, 2019

7.3K

Non-specific pleuritis in patients with active malignancy.

Erik Vakil1,2, David Ost2, Macarena R Vial3

  • 1McGovern Medical School, University of Texas Health Sciences Center at Houston, Houston, TX, USA.

Respirology (Carlton, Vic.)
|October 13, 2017
PubMed
Summary
This summary is machine-generated.

Pleuroscopy biopsies negative for malignancy in patients with active cancer are often non-specific pleuritis. Further clinical review identified causes for this pleuritis in most cases, clarifying outcomes.

Keywords:
malignant pleural effusionpleural endoscopypleuritispleuroscopypulmonary eosinophilia

More Related Videos

Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model
09:31

Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model

Published on: October 2, 2015

9.7K
Near Infrared Photoimmunotherapy for Mouse Models of Pleural Dissemination
05:39

Near Infrared Photoimmunotherapy for Mouse Models of Pleural Dissemination

Published on: February 9, 2021

3.7K

Related Experiment Videos

Last Updated: Feb 21, 2026

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
07:54

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice

Published on: December 21, 2019

7.3K
Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model
09:31

Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model

Published on: October 2, 2015

9.7K
Near Infrared Photoimmunotherapy for Mouse Models of Pleural Dissemination
05:39

Near Infrared Photoimmunotherapy for Mouse Models of Pleural Dissemination

Published on: February 9, 2021

3.7K

Area of Science:

  • Pulmonology
  • Oncology
  • Pathology

Background:

  • Pleuroscopy is crucial for diagnosing malignant pleural effusion when cytology is negative.
  • Non-malignant biopsy results in patients with known cancer raise concerns for false-negative pleuroscopy findings.
  • This study addresses the outcomes of patients with active malignancy who received a non-malignant pleuroscopy diagnosis.

Purpose of the Study:

  • To determine the outcomes of patients with active malignancy and a non-malignant diagnosis on pleuroscopy.
  • To investigate the causes and implications of non-specific pleuritis in this patient group.

Main Methods:

  • Retrospective review of 199 pleuroscopy cases (January 2005-January 2015).
  • Biopsies categorized as malignant, eosinophilic pleuritis, or non-specific pleuritis.
  • Non-specific pleuritis cases further classified based on follow-up, treatment history, or other etiological factors.

Main Results:

  • Of 172 patients with active malignancy, 73 (42%) had malignant histopathology.
  • Non-specific pleuritis was found in 90 (52%) patients; 3 were later diagnosed with malignancy.
  • Identified causes for non-specific pleuritis included chemotherapy-induced (24), radiation-induced (27), other paramalignant (11), and benign (3); 31 were idiopathic.

Conclusions:

  • Malignant pleural disease prevalence was lower than anticipated in this cohort.
  • Non-specific pleuritis was the most common non-malignant finding.
  • Clinical review successfully identified causes for non-specific pleuritis in most patients, aiding outcome determination.