Related Experiment Videos
Retracted: Effects of Whey Peptides on Cardiovascular Disease Risk Factors
Joel J Pins1, Joseph M Keenan1
1From the Department of Family Medicine and Community Health, University of Minnesota Medical School, Hypertension and Cholesterol Research Center, Minneapolis, MN.
Journal of Clinical Hypertension (Greenwich, Conn.)
|October 13, 2017
Summary
Hydrolyzed whey protein supplements containing bioactive peptides significantly reduced blood pressure in adults with prehypertension or stage 1 hypertension. This whey protein intervention also improved blood lipids and C-reactive protein levels.
Area of Science:
- Nutrition Science
- Cardiovascular Health
- Biochemistry
Background:
- Previous research indicates milk-derived peptides possess blood pressure-lowering properties.
- Hypertension remains a significant global health concern, necessitating effective management strategies.
Purpose of the Study:
- To evaluate the efficacy of a hydrolyzed whey protein supplement, rich in bioactive peptides, on blood pressure reduction.
- To assess the impact of this supplement on blood lipids and inflammatory markers.
Main Methods:
- A 6-week randomized controlled trial involving 30 prehypertensive or stage 1 hypertensive subjects.
- Participants received either 20 g/d of hydrolyzed whey protein (active) or unmodified whey protein (control).
- Evaluations included blood pressure, blood lipids, safety parameters, and dietary intake, with a 4-week follow-up period.
Main Results:
- The active treatment group experienced a significant reduction in systolic blood pressure (8.0±3.2 mm Hg) and diastolic blood pressure (5.5±2.1 mm Hg) compared to the control group (P<.05).
- Significant improvements were observed in low-density lipoprotein cholesterol and high-sensitivity C-reactive protein levels in the treatment group.
- No significant adverse effects were reported during the study or follow-up.
Conclusions:
- Hydrolyzed whey protein, particularly its bioactive peptide components, demonstrates a viable therapeutic potential for managing prehypertension and stage 1 hypertension.
- Whey-derived peptides may offer a beneficial dietary approach to improving cardiovascular risk factors, including blood pressure and lipid profiles.