Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optic nerve head problem.

Rohan Verma1, Kevin C Chen1, Hema L Ramkumar1

  • 1Department of Ophthalmology, University of California, San Diego, California, USA.

Survey of Ophthalmology
|October 13, 2017
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reverse magnetic resonance signal from intraocular hemorrhage.

Retinal cases & brief reports·2014
Same author

Intravitreal bevacizumab (avastin) and ranibizumab (lucentis) for choroidal neovascularization overlying choroidal osteoma.

Retinal cases & brief reports·2014
Same author

Retinoblastoma in a 48-year-old woman.

Retinal cases & brief reports·2014
Same author

Neovascular glaucoma as the presenting sign of metastatic small cell lung carcinoma.

Retinal cases & brief reports·2014
Same author

Partial regression of vitreoretinal lymphoma after fine needle aspiration biopsy.

Retinal cases & brief reports·2014
Same author

Sclerochoroidal calcification in a patient with chronic hypercalcemia from undiagnosed parathyroid adenoma.

Retinal cases & brief reports·2014
Same journal

Trends in pediatric uveitis: A systematic review and meta-epidemiological investigation of geographic, economic, and climate factors.

Survey of ophthalmology·2026
Same journal

Efficacy and safety of different intraocular therapies for non-infectious uveitis: A network meta-analysis.

Survey of ophthalmology·2026
Same journal

Macular telangiectasia masqueraders.

Survey of ophthalmology·2026
Same journal

Utilization of anterior segment optical coherence tomography in childhood glaucoma: A systematic review.

Survey of ophthalmology·2026
Same journal

Peripapillary pachychoroid syndrome: Clinical and imaging features, diagnostic differentiation and therapeutic strategies.

Survey of ophthalmology·2026
Same journal

Prognostic factors and postoperative outcomes in pediatric cataract patients: A systematic review and meta-analysis.

Survey of ophthalmology·2026
See all related articles

A 68-year-old woman with a history of breast cancer developed optic disk metastasis. Imaging confirmed a peripapillary mass, diagnosed as breast carcinoma metastasis to the optic nerve.

Area of Science:

  • Ophthalmology
  • Oncology
  • Medical Imaging

Background:

  • Breast cancer is a common malignancy with potential for distant metastasis.
  • Optic nerve involvement is a rare but serious complication of metastatic cancer.
  • Metastasis to the optic disk can present with visual disturbances.

Observation:

  • A 68-year-old woman with a history of breast cancer and bone metastases presented with blurred vision in the left eye.
  • Ophthalmic examination revealed an isolated peripapillary mass on the optic nerve head.
  • Advanced imaging techniques including angiography, ultrasound, OCT, and MRI were utilized.

Findings:

  • Indocyanine green and fluorescein angiography showed vascularity and leakage within the mass.
  • B-scan ultrasound identified a hyperechoic, elevated nodular mass on the optic disc.
Keywords:
breast carcinomaocular metastasisoptic nerve head massoptic nerve metastasis

Related Experiment Videos

  • Spectral-domain optical coherence tomography revealed a mass composed of spherules.
  • Brain MRI confirmed metastatic tumors, consistent with systemic spread.
  • Implications:

    • This case highlights the importance of considering metastatic disease in patients with a history of cancer presenting with ocular symptoms.
    • Optic disk metastasis from breast carcinoma requires prompt diagnosis and management.
    • Multimodal imaging is crucial for characterizing optic nerve head masses and guiding treatment decisions.