Related Experiment Video
Updated: Jul 21, 2026

14:56
An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
Published on: January 27, 2010
Predictors of Responsivity to Interdisciplinary Pain Management
Melissa A Day1,2, Melissa Brinums1,2, Nathan Craig3,2
1School of Psychology.
Pain Medicine (Malden, Mass.)
|October 13, 2017
Summary
Interdisciplinary pain management (IPM) improved physical, psychological, and social outcomes for many chronic pain patients. Higher baseline depression, nociceptive pain, and older age predicted better treatment response.
Area of Science:
- Pain Management
- Rehabilitation Medicine
- Clinical Psychology
Background:
- Identifying predictors of treatment success in interdisciplinary pain management (IPM) is crucial for optimizing patient outcomes.
- Patient-treatment matching algorithms can enhance the effectiveness of chronic pain rehabilitation programs.
Purpose of the Study:
- To determine which patient characteristics predict successful outcomes in an interdisciplinary pain management (IPM) program.
- To identify subgroups of patients most likely to benefit from IPM to inform treatment matching.
Main Methods:
- Prospective study of 163 adults admitted to a two-week IPM program.
- Collected self-report questionnaires and physical performance measures at program entry and completion.
- Utilized group-level and individual-level analyses, including multivariate analysis of variance and logistic regression.
Main Results:
- Significant improvements observed across psychological, social, and physical domains, with up to 50% achieving clinically meaningful improvements.
- Higher baseline depression, anxiety, stress, and pain catastrophizing predicted better group-level outcomes.
- Individuals with higher baseline depression were most likely to show significant individual-level improvement. Nociceptive pain and older age were associated with greater multidomain response.
Conclusions:
- Interdisciplinary pain management (IPM) leads to significant improvements in physical, psychological, and social outcomes for a substantial proportion of patients.
- High baseline depression reliably predicts individual-level improvement in IPM.
- Nociceptive pain and older age are associated with the greatest response across multiple outcome domains.

