Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

5.1K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
5.1K
Carbohydrate Metabolism01:36

Carbohydrate Metabolism

14.5K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
14.5K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

2.4K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.4K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

3.8K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.8K
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

5.6K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
5.6K
Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

1.1K
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
1.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Weight-loss practices and dietary quality in Chinese adolescents.

BMC public health·2026
Same author

Association Between Lifecourse Socioeconomic Status and Cognitive Impairment Among Chinese Older Adults: The Mediating Role of Leisure Activity.

Journal of gerontological social work·2026
Same author

A phenomenological study on psychological resilience among medical vocational college freshmen.

Frontiers in psychiatry·2026
Same author

Bidirectional association between breast cancer and cardiovascular disease: Longitudinal analysis of UK Biobank data.

Atherosclerosis·2026
Same author

Construction of indicator system and comprehensive evaluation of high-quality development of cultural tourism integration in revolutionary base areas.

PloS one·2026
Same author

Association Between Salt Intake and Body Adiposity in Chinese Population: A Repeated-Measures Cohort Study.

Nutrients·2026

Related Experiment Video

Updated: Feb 21, 2026

Preparation of Washed Human Platelets for Quantitative Metabolic Flux Studies
07:06

Preparation of Washed Human Platelets for Quantitative Metabolic Flux Studies

Published on: January 10, 2025

1.2K

The Relationship between Type 2 Diabetes and Platelet Indicators.

Xiangyu Chen1, Le Fang1, Hongbo Lin2

  • 1Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, P.R. China.

Iranian Journal of Public Health
|October 14, 2017
PubMed
Summary

Mean platelet volume (MPV) is linked to type 2 diabetes risk, unlike platelet count (PLT) and platelet distribution width (PDW). Higher MPV levels indicate an increased risk of developing diabetes.

Keywords:
Diabetes mellitusMean platelet volumePlatelet countPlatelet distribution width

More Related Videos

Experimental and Imaging Techniques for Examining Fibrin Clot Structures in Normal and Diseased States
07:09

Experimental and Imaging Techniques for Examining Fibrin Clot Structures in Normal and Diseased States

Published on: April 1, 2015

12.0K
A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes
05:18

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

Published on: February 17, 2023

5.9K

Related Experiment Videos

Last Updated: Feb 21, 2026

Preparation of Washed Human Platelets for Quantitative Metabolic Flux Studies
07:06

Preparation of Washed Human Platelets for Quantitative Metabolic Flux Studies

Published on: January 10, 2025

1.2K
Experimental and Imaging Techniques for Examining Fibrin Clot Structures in Normal and Diseased States
07:09

Experimental and Imaging Techniques for Examining Fibrin Clot Structures in Normal and Diseased States

Published on: April 1, 2015

12.0K
A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes
05:18

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes

Published on: February 17, 2023

5.9K

Area of Science:

  • Endocrinology
  • Hematology
  • Epidemiology

Background:

  • Large-scale studies on type 2 diabetes and platelet indicators are scarce, particularly in Asian populations.
  • Previous research often involved small sample sizes, limiting generalizability.

Purpose of the Study:

  • To investigate the association between type 2 diabetes and key platelet parameters: mean platelet volume (MPV), platelet count (PLT), and platelet distribution width (PDW).
  • To assess MPV as a potential independent risk factor for diabetes mellitus.

Main Methods:

  • Cross-sectional analysis of health examination data from 20,128 participants.
  • Utilized routine laboratory results obtained via automatic hematology analyzer.

Main Results:

  • No significant differences in platelet distribution width (PDW) or platelet count (PLT) were observed between diabetic and non-diabetic groups.
  • Mean platelet volume (MPV) was significantly higher in individuals with type 2 diabetes.
  • Increased MPV levels were identified as an independent risk factor for diabetes, with risk escalating at higher MPV values.

Conclusions:

  • Platelet count (PLT) and platelet distribution width (PDW) are not associated with type 2 diabetes.
  • Mean platelet volume (MPV) is independently associated with the presence of type 2 diabetes, suggesting its potential as a predictive biomarker.