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Juvenile Trabecular Ossifying Fibroma.

Ahmed S Sultan1, Michael K Schwartz2, John F Caccamese3

  • 1Department of Oncology and Diagnostic Sciences, School of Dentistry, University of Maryland, Baltimore, MD, 21201, USA. asultan@umaryland.edu.

Head and Neck Pathology
|October 14, 2017
PubMed
Summary
This summary is machine-generated.

Juvenile ossifying fibroma (JOF) is a rare, aggressive fibro-osseous neoplasm. This article details a case of juvenile trabecular ossifying fibroma (JTOF) in the mandible, emphasizing diagnostic correlations.

Keywords:
Benign fibro-osseous lesionsJuvenile trabecular ossifying fibromaMandibleOral cavityOssifying fibroma

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Area of Science:

  • Oral and Maxillofacial Pathology
  • Radiology
  • Oncology

Background:

  • Benign fibro-osseous lesions in the maxillofacial region are diverse and can present overlapping histological features.
  • Ossifying fibroma is a rare neoplasm within this group, with juvenile ossifying fibroma (JOF) being an aggressive subtype.
  • JOF typically affects individuals in their first or second decade of life and has two variants: juvenile trabecular ossifying fibroma (JTOF) and juvenile psammomatoid ossifying fibroma (JPOF).

Observation:

  • Juvenile trabecular ossifying fibroma (JTOF) is characterized by a proliferation of cellular fibroblastic tissue intertwined with woven bone trabeculae.
  • Histological presentations of JTOF can vary significantly.
  • Accurate differentiation from other fibro-osseous lesions necessitates correlation of clinical and radiographic findings.

Findings:

  • This article presents a case study of JTOF affecting the mandible.
  • The case highlights the importance of integrating radiological and pathological data for diagnosis.
  • The specific histological features of the presented JTOF case are discussed in relation to diagnostic criteria.

Implications:

  • Accurate diagnosis of JTOF is crucial due to its aggressive nature and potential for rapid growth.
  • Understanding the histological variants and diagnostic challenges of JOF aids clinicians in appropriate management.
  • This case report contributes to the literature on maxillofacial fibro-osseous lesions, particularly JTOF.