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Related Experiment Videos

A Method to Quantitatively Assess Dermal Exposure to Volatile Organic Compounds.

Matteo Creta1, Katrien Poels1, Laurens Thoelen1

  • 1Centre for Environment and Health, Department of Public Health and Primary Care, KU Leuven, Kapucijnenvoer 35 - 6th floor box 7001, 3000 , Leuven, Belgium, Belgium.

Annals of Work Exposures and Health
|October 14, 2017
PubMed
Summary

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A new method using activated charcoal cloth (ACC) accurately quantifies worker skin exposure to 181 volatile organic compounds (VOCs). This sensitive approach improves occupational safety by enabling better dermal exposure assessments.

Area of Science:

  • Occupational Health and Safety
  • Environmental Chemistry
  • Analytical Chemistry

Background:

  • Assessing dermal exposure to volatile organic compounds (VOCs) is crucial in industrial settings.
  • Current methodologies for quantifying skin exposure to VOCs lack validation.
  • Volatile organic compounds are widely used, necessitating accurate exposure assessment tools.

Purpose of the Study:

  • To develop and validate a sensitive methodology for quantitatively assessing dermal exposure to 181 VOCs.
  • To evaluate the performance of activated charcoal cloth (ACC) as a sampling material for VOCs.
  • To establish a reliable method for measuring skin exposure to VOCs in occupational environments.

Main Methods:

  • Development of a quantitative methodology utilizing activated charcoal cloth (ACC) for VOC sampling.
Keywords:
activated charcoal clothcharcoal padsdermal exposure assessmentoccupational hygienepermea-tec sensorsvolatile organic compounds

Related Experiment Videos

  • Testing desorption efficiency (DE) of 181 VOCs across various concentrations.
  • Evaluating storage stability of VOCs on ACC, including low-temperature storage.
  • Controlled environment tests to assess ACC's linearity with increasing VOC air concentrations.

    • Main Results:

    • The ACC methodology demonstrated high sensitivity and quantitative accuracy for 181 VOCs.
    • Most VOCs exhibited a constant desorption efficiency of approximately 100%.
    • Concentration-dependent desorption was observed for seven VOCs, described by a Dubinin-Raduskevich isotherm.
    • Good storage stability was noted for most VOCs on ACC, particularly at -80°C, with n-pentane showing a ~40% decrease after one month.
    • ACC showed high linearity (R2 ≥ 0.812) in reflecting airborne VOC concentrations, except for gamma-butyrolactone (R2 = 0.570).

    Conclusions:

    • Activated charcoal cloth (ACC) is a suitable and sensitive material for quantitatively assessing dermal exposure to a wide range of VOCs.
    • The developed methodology provides a validated tool for detailed dermal exposure studies in occupational settings.
    • This advancement will lead to improved risk assessment and management of skin exposure to VOCs in the workplace.