Consecutive Photoinduced Electron Transfer Enabled Generation and Reactivity of Trifluoroacetyl Radical Equivalent
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Published on: April 22, 2016
Parashuram Sharma1, Nisha Rawat1, Shashwat Bishwanathan2
1Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur208016, India.
Abstract:
The development of a photochemical strategy for the generation of a polarity-reversed trifluoroacetyl radical equivalent using the consecutive photoinduced electron transfer (ConPET) mechanism is described employing the commonly available 4CzIPN photocatalyst. This three-component, mild, and efficient protocol achieves the difunctionalization of a broad selection of alkenes and is compatible with late-stage functionalization of structurally complex unsaturated coupling partners. The proposed ConPET mechanism is corroborated by detailed mechanistic studies.
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