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Published on: October 21, 2017
Nutritional Needs and Support for Children with Chronic Liver Disease
Christine H Yang1, Brandon J Perumpail2, Eric R Yoo3
1Division of Pediatric Gastroenterology, Hepatology and Nutrition, Lucile Packard Children's Hospital, Palo Alto, Stanford, CA 94304, USA. christine.yang@stanford.edu.
Nutrients
|October 17, 2017
Summary
Malnutrition is common in children with chronic liver disease (CLD), affecting growth and neurodevelopment. Early intervention by a multidisciplinary team is crucial for nutritional rehabilitation and improving liver transplant outcomes.
Area of Science:
- Pediatric Gastroenterology and Hepatology
- Pediatric Nutrition
- Clinical Pediatrics
Background:
- Malnutrition is prevalent in pediatric patients with chronic liver disease (CLD).
- Nutritional deficiencies negatively impact neurocognitive development and growth in these children.
- Malnutrition is a significant predictor of adverse outcomes, including increased morbidity and mortality, in children undergoing liver transplantation.
Purpose of the Study:
- To review the multifactorial causes of malnutrition in children with CLD.
- To define the specific nutritional requirements for children suffering from CLD.
- To discuss strategies for optimizing nutritional status and improving outcomes in this vulnerable population.
Main Methods:
- Comprehensive literature review.
- Analysis of existing studies on malnutrition in pediatric chronic liver disease.
- Synthesis of data on nutritional needs and management strategies.
Main Results:
- Infants with CLD are especially vulnerable to malnutrition due to limited physiological reserves.
- A multidisciplinary team approach is recommended for early nutritional intervention.
- Aggressive management is necessary to correct nutritional deficiencies.
Conclusions:
- Optimizing nutrition is essential for children with CLD to support growth, development, and transplant success.
- Early and comprehensive nutritional support can mitigate negative impacts of malnutrition.
- Multidisciplinary care is key to achieving nutritional rehabilitation in pediatric liver disease.
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