Related Experiment Videos
Visible-light-mediated cleavage of polymer chains under physiological conditions via quinone photoreduction and
Vinh X Truong1, Fanyi Li, Francesca Ercole
1Department of Materials Science and Engineering, Monash Institute of Medical Engineering, Monash University, Clayton, 3800 VIC, Australia. vinh.truong@monash.edu john.forsythe@monash.edu.
Chemical Communications (Cambridge, England)
|October 17, 2017
Abstract:
We introduce a click and visible-light triggered unclick approach via thio-bromo reaction and hydroquinone photoreduction/trimethyl lock cleavage for polymer modifications. Both reactions can be carried out in water and at ambient temperature, enabling preparation of bioorthogonal hydrogels for encapsulation and controlled release of various cells.