Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Where Is the "Optimal" Fontan Hemodynamics?

Hideo Ohuchi1

  • 1Departments of Pediatric Cardiology and Adult Congenital Heart Disease, National Cerebral and Cardiovascular Center, Suita, Japan. hohuchi@hsp.ncvc.go.jp.

Korean Circulation Journal
|October 17, 2017
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mac-2 Binding Protein Glycosylation Isomer (M2BPGi) Reflects Global Pathophysiology and Predicts All-Cause Morbidity and Mortality in Patients With Fontan Circulation.

Circulation journal : official journal of the Japanese Circulation Society·2026
Same author

Emergency and Non-Referral Admissions as Predictors of Hospital Mortality Among Adults with Congenital Heart Diseases: A Nationwide Claim-Based Registry Study in Japan.

Healthcare (Basel, Switzerland)·2026
Same author

Electrophysiological outcomes of radiofrequency ablation for supraventricular tachycardias in patients with congenitally corrected transposition of the great arteries.

Heart rhythm O2·2026
Same author

Unplanned Hospitalization Due to All-Cause Morbidity and Its Real-World Management Practices in Patients With Fontan Circulation.

Journal of the American Heart Association·2025
Same author

Diagnosis, management, and outcome of heart failure in congenitally corrected transposition of the great arteries (ccTGA)-a narrative review.

Cardiovascular diagnosis and therapy·2025
Same author

Benefits of Chronic Atrial Pacing in Fontan Physiology with Sinus Node Dysfunction and Preserved Ejection Fraction: Novel Therapeutic Approach for Failing Fontan.

Pediatric cardiology·2025

Fontan circulation management aims for smooth adjustment and long-term stabilization. Understanding failing Fontan hemodynamics is crucial for improving outcomes in survivors with congenital heart disease.

Area of Science:

  • Cardiology
  • Pediatric Cardiology
  • Congenital Heart Disease

Background:

  • Fontan circulation presents unique hemodynamic challenges, differing significantly from normal biventricular physiology.
  • Achieving smooth adjustment and long-term hemodynamic stabilization are critical goals in Fontan circulation therapy.
  • Failure to meet these goals leads to "failed" Fontan circulation with poor prognosis.

Purpose of the Study:

  • To investigate the clinical and hemodynamic characteristics of early and late failing Fontan survivors.
  • To explore the association between these characteristics and all-cause mortality.
  • To provide insights into Fontan pathophysiology for improved long-term management strategies.

Main Methods:

  • Retrospective analysis of clinical data from Fontan survivors.
Keywords:
Cardiac outputFontan procedureHemodynamicsMortalityVascular resistance

Related Experiment Videos

  • Detailed hemodynamic assessment in patients experiencing Fontan failure.
  • Statistical analysis to correlate clinical and hemodynamic factors with mortality.

    • Main Results:

    • Identified distinct clinical and hemodynamic profiles for early versus late Fontan failure.
    • Established a significant association between specific hemodynamic parameters and all-cause mortality.
    • Highlighted the complexity of Fontan pathophysiology and its impact on long-term outcomes.

    Conclusions:

    • Understanding the characteristics of failing Fontan circulation is essential for developing effective management strategies.
    • Further research into optimal hemodynamics is needed to guide patient care and improve survival.
    • This study provides valuable data for establishing a management framework for long-term hemodynamic stabilization in Fontan survivors.