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Related Experiment Videos

Metoclopramide and ureteric colic.

J L Hedenbro1, A M Olsson

  • 1Department of Surgery, University of Lund, Sweden.

Acta Chirurgica Scandinavica
|July 1, 1988
PubMed
Summary
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Metoclopramide effectively reduces pain from ureteric colic, matching narcotic drug efficacy. It offers a safe alternative when other pain relievers cannot be used.

Area of Science:

  • Pharmacology
  • Urology
  • Pain Management

Background:

  • Ureteric colic causes severe pain.
  • Current treatments include prostaglandin synthesis inhibitors and narcotics.
  • Alternative analgesics are needed, especially when standard treatments are contraindicated.

Purpose of the Study:

  • To compare the analgesic efficacy of metoclopramide with a narcotic combination drug (Spasmofen).
  • To evaluate the safety profile of metoclopramide in patients with ureteric colic.

Main Methods:

  • A double-blind study was conducted.
  • Forty patients diagnosed with ureteric colic participated.
  • Pain reduction was assessed comparing metoclopramide and Spasmofen.

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Main Results:

  • Both metoclopramide and Spasmofen demonstrated equal pain-reducing capacity.
  • No serious adverse events were observed for either drug.
  • Metoclopramide was well-tolerated by patients.

Conclusions:

  • Metoclopramide is a viable alternative for pain relief in ureteric colic.
  • It is particularly useful when prostaglandin synthesis inhibitors or narcotics are contraindicated.
  • The drug offers comparable efficacy and a favorable safety profile.